ENSMUSG00000031950


Mus musculus

Features
Gene ID: ENSMUSG00000031950
  
Biological name :Gabarapl2
  
Synonyms : Gabarapl2 / Gamma-aminobutyric acid receptor-associated protein-like 2 / P60521
  
Possible biological names infered from orthology : GABA type A receptor associated protein like 2 / P60520
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: E1
Gene start: 111940703
Gene end: 111953612
  
Corresponding Affymetrix probe sets: 10528546 (MoGene1.0st)   10575616 (MoGene1.0st)   1423187_at (Mouse Genome 430 2.0 Array)   1441376_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034428
NCBI entrez gene - 93739     See in Manteia.
MGI - MGI:1890602
RefSeq - NM_026693
RefSeq Peptide - NP_080969
swissprot - P60521
Ensembl - ENSMUSG00000031950
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabarapl2ENSDARG00000027200Danio rerio
 GABARAPL2ENSGALG00000003208Gallus gallus
 P60520ENSG00000034713Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R3R8 / Gabarapl1 / Gamma-aminobutyric acid receptor-associated protein-like 1 / Q9H0R8* / GABA type A receptor associated protein like 1*ENSMUSG0000003016161
Q9DCD6 / Gabarap / Gamma-aminobutyric acid receptor-associated protein / O95166* / GABA type A receptor-associated protein*ENSMUSG0000001856757
Q91VR7 / Map1lc3a / Microtubule-associated proteins 1A/1B light chain 3A / Q9H492* / microtubule associated protein 1 light chain 3 alpha*ENSMUSG0000002760240
Q9CQV6 / Map1lc3b / Microtubule-associated proteins 1A/1B light chain 3B / A6NCE7* / Q9GZQ8* / MAP1LC3B2* / microtubule associated protein 1 light chain 3 beta* / microtubule associated pr...ENSMUSG0000003181238


Protein motifs (from Interpro)
Interpro ID Name
 IPR004241  Autophagy protein Atg8 ubiquitin-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport ISO
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome ISO
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005419 hypoalbuminemia "blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Fustm1.1(KOMP)Vlcg/Fustm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Fustm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039201 A1A5B6 / Tbc1d25 / TBC1 domain family member 25 / Q3MII6*  / reaction / complex






 

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