ENSMUSG00000018567


Mus musculus

Features
Gene ID: ENSMUSG00000018567
  
Biological name :Gabarap
  
Synonyms : Gabarap / Gamma-aminobutyric acid receptor-associated protein / Q9DCD6
  
Possible biological names infered from orthology : GABA type A receptor-associated protein / O95166
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 69991143
Gene end: 69994951
  
Corresponding Affymetrix probe sets: 10377689 (MoGene1.0st)   1416937_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000104233
Ensembl peptide - ENSMUSP00000018711
NCBI entrez gene - 56486     See in Manteia.
MGI - MGI:1861742
RefSeq - NM_019749
RefSeq Peptide - NP_062723
swissprot - B1AR50
swissprot - Q9DCD6
Ensembl - ENSMUSG00000018567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabarapaENSDARG00000035557Danio rerio
 O95166ENSG00000170296Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8R3R8 / Gabarapl1 / Gamma-aminobutyric acid receptor-associated protein-like 1 / Q9H0R8* / GABA type A receptor associated protein like 1*ENSMUSG0000003016186
P60521 / Gabarapl2 / Gamma-aminobutyric acid receptor-associated protein-like 2 / P60520* / GABA type A receptor associated protein like 2*ENSMUSG0000003195057
Q9CQV6 / Map1lc3b / Microtubule-associated proteins 1A/1B light chain 3B / A6NCE7* / Q9GZQ8* / MAP1LC3B2* / microtubule associated protein 1 light chain 3 beta* / microtubule associated pr...ENSMUSG0000003181232
Q91VR7 / Map1lc3a / Microtubule-associated proteins 1A/1B light chain 3A / Q9H492* / microtubule associated protein 1 light chain 3 alpha*ENSMUSG0000002760231


Protein motifs (from Interpro)
Interpro ID Name
 IPR004241  Autophagy protein Atg8 ubiquitin-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000226 microtubule cytoskeleton organization IDA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IDA
 cellular_componentGO:0005776 autophagosome ISO
 cellular_componentGO:0005790 smooth endoplasmic reticulum IDA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005875 microtubule associated complex IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005930 axoneme IDA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097225 sperm midpiece IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA
 molecular_functionGO:0050811 GABA receptor binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

Allelic Composition: GabarapGt(OST31915)Lex/GabarapGt(OST31915)Lex
Genetic Background: involves: 129S5/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039201 A1A5B6 / Tbc1d25 / TBC1 domain family member 25 / Q3MII6*  / complex / reaction






 

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contact: otassy@igbmc.fr