ENSG00000170296


Homo sapiens

Features
Gene ID: ENSG00000170296
  
Biological name :GABARAP
  
Synonyms : GABARAP / GABA type A receptor-associated protein / O95166
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.1
Gene start: 7240014
Gene end: 7242770
  
Corresponding Affymetrix probe sets: 200645_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460855
Ensembl peptide - ENSP00000461882
Ensembl peptide - ENSP00000306866
Ensembl peptide - ENSP00000458476
Ensembl peptide - ENSP00000459345
Ensembl peptide - ENSP00000460489
NCBI entrez gene - 11337     See in Manteia.
OMIM - 605125
RefSeq - NM_007278
RefSeq Peptide - NP_009209
swissprot - I3L236
swissprot - I3L3J4
swissprot - H6UMI1
swissprot - O95166
swissprot - Q6IAW1
Ensembl - ENSG00000170296
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabarapaENSDARG00000035557Danio rerio
 Q9DCD6ENSMUSG00000018567Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H0R8 / GABARAPL1 / GABA type A receptor associated protein like 1ENSG0000013911286
P60520 / GABARAPL2 / GABA type A receptor associated protein like 2ENSG0000003471357
Q9BXW4 / MAP1LC3C / microtubule associated protein 1 light chain 3 gammaENSG0000019776938
Q9GZQ8 / MAP1LC3B / microtubule associated protein 1 light chain 3 betaENSG0000014094132
A6NCE7 / MAP1LC3B2 / microtubule associated protein 1 light chain 3 beta 2ENSG0000025810231
Q9H492 / MAP1LC3A / microtubule associated protein 1 light chain 3 alphaENSG0000010146029


Protein motifs (from Interpro)
Interpro ID Name
 IPR004241  Autophagy protein Atg8 ubiquitin-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006605 protein targeting TAS
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IDA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0097352 autophagosome maturation TAS
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0000421 autophagosome membrane TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005790 smooth endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005875 microtubule associated complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005930 axoneme IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0044297 cell body IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0097225 sperm midpiece IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0048487 beta-tubulin binding IDA
 molecular_functionGO:0050811 GABA receptor binding IPI


Pathways (from Reactome)
Pathway description
Macroautophagy
TBC/RABGAPs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000068354 Q3MII6 / TBC1D25 / TBC1 domain family member 25  / reaction / complex






 

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