ENSG00000140941


Homo sapiens

Features
Gene ID: ENSG00000140941
  
Biological name :MAP1LC3B
  
Synonyms : MAP1LC3B / microtubule associated protein 1 light chain 3 beta / Q9GZQ8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.2
Gene start: 87383995
Gene end: 87404779
  
Corresponding Affymetrix probe sets: 208785_s_at (Human Genome U133 Plus 2.0 Array)   208786_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454293
Ensembl peptide - ENSP00000457141
Ensembl peptide - ENSP00000457225
Ensembl peptide - ENSP00000268607
NCBI entrez gene - 81631     See in Manteia.
OMIM - 609604
RefSeq - NM_022818
RefSeq Peptide - NP_073729
swissprot - Q9GZQ8
swissprot - H3BM99
swissprot - H3BTE7
swissprot - H3BTL1
swissprot - Q658J6
Ensembl - ENSG00000140941
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map1lc3bENSDARG00000101127Danio rerio
 MAP1LC3BENSGALG00000043105Gallus gallus
 Q9CQV6ENSMUSG00000031812Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NCE7 / MAP1LC3B2 / microtubule associated protein 1 light chain 3 beta 2ENSG0000025810299
Q9H492 / MAP1LC3A / microtubule associated protein 1 light chain 3 alphaENSG0000010146072
Q9BXW4 / MAP1LC3C / microtubule associated protein 1 light chain 3 gammaENSG0000019776954
P60520 / GABARAPL2 / GABA type A receptor associated protein like 2ENSG0000003471336
Q9H0R8 / GABARAPL1 / GABA type A receptor associated protein like 1ENSG0000013911230
O95166 / GABARAP / GABA type A receptor-associated proteinENSG0000017029630


Protein motifs (from Interpro)
Interpro ID Name
 IPR004241  Autophagy protein Atg8 ubiquitin-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IGI
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0009267 cellular response to starvation IDA
 biological_processGO:0016236 macroautophagy IDA
 biological_processGO:0097352 autophagosome maturation IDA
 cellular_componentGO:0000421 autophagosome membrane TAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005776 autophagosome ISS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005930 axoneme ISS
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI


Pathways (from Reactome)
Pathway description
Macroautophagy
Pink/Parkin Mediated Mitophagy
TBC/RABGAPs
Receptor Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000145782 ATG12 / O94817 / autophagy related 12  / reaction / complex
 ENSG00000057663 ATG5 / Q9H1Y0 / autophagy related 5  / reaction / complex
 ENSG00000069509 FUNDC1 / Q8IVP5 / FUN14 domain containing 1  / reaction / complex
 ENSG00000068354 Q3MII6 / TBC1D25 / TBC1 domain family member 25  / reaction / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr