ENSG00000069509


Homo sapiens

Features
Gene ID: ENSG00000069509
  
Biological name :FUNDC1
  
Synonyms : FUN14 domain containing 1 / FUNDC1 / Q8IVP5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: p11.3
Gene start: 44523639
Gene end: 44543001
  
Corresponding Affymetrix probe sets: 235346_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367284
NCBI entrez gene - 139341     See in Manteia.
OMIM - 300871
RefSeq - NM_173794
RefSeq Peptide - NP_776155
swissprot - Q8IVP5
Ensembl - ENSG00000069509
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fundc1ENSDARG00000040822Danio rerio
 E1BWM5ENSGALG00000028187Gallus gallus
 Fundc1ENSMUSG00000025040Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FUNDC2 / Q9BWH2 / FUN14 domain containing 2ENSG0000016577554


Protein motifs (from Interpro)
Interpro ID Name
 IPR007014  FUN14
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion IMP
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0010243 response to organonitrogen compound IEA
 biological_processGO:0016236 macroautophagy TAS
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Receptor Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101266 P68400 / CSNK2A1 / casein kinase 2 alpha 1  / reaction
 ENSG00000070770 P19784 / CSNK2A2 / casein kinase 2 alpha 2  / reaction
 ENSG00000177169 ULK1 / O75385 / unc-51 like autophagy activating kinase 1  / reaction
 ENSG00000247077 PGAM5 / Q96HS1 / PGAM family member 5, mitochondrial serine/threonine protein phosphatase  / reaction
 ENSG00000197122 SRC / P12931 / SRC proto-oncogene, non-receptor tyrosine kinase  / reaction
 ENSG00000204435 CSNK2B / P67870 / casein kinase 2 beta  / reaction
 ENSG00000101460 Q9H492 / MAP1LC3A / microtubule associated protein 1 light chain 3 alpha  / reaction / complex
 ENSG00000145782 ATG12 / O94817 / autophagy related 12  / complex / reaction
 ENSG00000140941 Q9GZQ8 / MAP1LC3B / microtubule associated protein 1 light chain 3 beta  / complex / reaction
 ENSG00000057663 ATG5 / Q9H1Y0 / autophagy related 5  / reaction / complex






 

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