ENSMUSG00000025040


Mus musculus

Features
Gene ID: ENSMUSG00000025040
  
Biological name :Fundc1
  
Synonyms : FUN14 domain-containing protein 1 / Fundc1 / Q9DB70
  
Possible biological names infered from orthology : FUN14 domain containing 1 / Q8IVP5
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A1.2
Gene start: 17556564
Gene end: 17572325
  
Corresponding Affymetrix probe sets: 10603785 (MoGene1.0st)   1424215_at (Mouse Genome 430 2.0 Array)   1453369_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026016
Ensembl peptide - ENSMUSP00000134878
Ensembl peptide - ENSMUSP00000135026
Ensembl peptide - ENSMUSP00000135183
NCBI entrez gene - 72018     See in Manteia.
MGI - MGI:1919268
RefSeq - NM_001313745
RefSeq - NM_001313746
RefSeq - NM_028058
RefSeq Peptide - NP_001300675
RefSeq Peptide - NP_082334
RefSeq Peptide - NP_001300674
swissprot - Q9DB70
swissprot - H3BJ77
swissprot - H3BJZ1
Ensembl - ENSMUSG00000025040
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fundc1ENSDARG00000040822Danio rerio
 E1BWM5ENSGALG00000028187Gallus gallus
 FUNDC1ENSG00000069509Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fundc2 / Q9D6K8 / FUN14 domain-containing protein 2 / Q9BWH2* / FUN14 domain containing 2*ENSMUSG0000003119854
1700034I23Rik / RIKEN cDNA 1700034I23 gene / FUNDC2* / Q9BWH2* / FUN14 domain containing 2*ENSMUSG0000007461953


Protein motifs (from Interpro)
Interpro ID Name
 IPR007014  FUN14
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000422 autophagy of mitochondrion IEA
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0010243 response to organonitrogen compound IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Receptor Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Arhgap35m1Bchd/Arhgap35tm1Jset
Genetic Background: involves: 129S2/SvPas * C3H/HeNCrl * C57BL/6J

Allelic Composition: Fundc1tm1a(KOMP)Wtsi/Y
Genetic Background: involves: C57BL/6 * C57BL/6N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000024387 Csnk2b / P67871 / Casein kinase II subunit beta / P67870* / casein kinase 2 beta*  / reaction
 ENSMUSG00000038160 Atg5 / Q99J83 / Autophagy protein 5 / Q9H1Y0* / autophagy related 5*  / complex / reaction
 ENSMUSG00000032905 Atg12 / Q9CQY1 / Ubiquitin-like protein ATG12 / O94817* / autophagy related 12*  / reaction / complex
 ENSMUSG00000027646 Src / P05480 / Neuronal proto-onco tyrosine-protein kinase Src / P12931* / SRC proto-oncogene, non-receptor tyrosine kinase*  / reaction
 ENSMUSG00000029512 Ulk1 / unc-51 like kinase 1 / O75385* / unc-51 like autophagy activating kinase 1*  / reaction
 ENSMUSG00000031812 Q9CQV6 / Map1lc3b / Microtubule-associated proteins 1A/1B light chain 3B / A6NCE7* / Q9GZQ8* / MAP1LC3B2* / microtubule associated protein 1 light chain 3 beta* / microtubule associated pr...  / complex / reaction
 ENSMUSG00000027602 Q91VR7 / Map1lc3a / Microtubule-associated proteins 1A/1B light chain 3A / Q9H492* / microtubule associated protein 1 light chain 3 alpha*  / complex / reaction
 ENSMUSG00000046707 O54833 / Csnk2a2 / Casein kinase II subunit alpha / P19784* / casein kinase 2 alpha 2*  / reaction
 ENSMUSG00000029500 Pgam5 / Q8BX10 / Serine/threonine-protein phosphatase PGAM5, mitochondrial / Q96HS1* / PGAM family member 5, mitochondrial serine/threonine protein phosphatase*  / reaction
 ENSMUSG00000101523 Q60737 / Gm10031 / predicted pseudogene 10031 / Q8NEV1* / P68400* / CSNK2A1* / CSNK2A3* / casein kinase 2 alpha 1* / casein kinase 2 alpha 3*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr