ENSMUSG00000027602


Mus musculus

Features
Gene ID: ENSMUSG00000027602
  
Biological name :Map1lc3a
  
Synonyms : Map1lc3a / Microtubule-associated proteins 1A/1B light chain 3A / Q91VR7
  
Possible biological names infered from orthology : microtubule associated protein 1 light chain 3 alpha / Q9H492
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: H1
Gene start: 155276297
Gene end: 155278073
  
Corresponding Affymetrix probe sets: 10477637 (MoGene1.0st)   1447883_x_at (Mouse Genome 430 2.0 Array)   1451290_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029128
NCBI entrez gene - 66734     See in Manteia.
MGI - MGI:1915661
RefSeq - NM_025735
RefSeq Peptide - NP_080011
swissprot - Q91VR7
Ensembl - ENSMUSG00000027602
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map1lc3aENSDARG00000033609Danio rerio
 ENSGALG00000038721Gallus gallus
 Q9H492ENSG00000101460Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9CQV6 / Map1lc3b / Microtubule-associated proteins 1A/1B light chain 3B / A6NCE7* / Q9GZQ8* / MAP1LC3B2* / microtubule associated protein 1 light chain 3 beta* / microtubule associated pr...ENSMUSG0000003181282
P60521 / Gabarapl2 / Gamma-aminobutyric acid receptor-associated protein-like 2 / P60520* / GABA type A receptor associated protein like 2*ENSMUSG0000003195039
Q8R3R8 / Gabarapl1 / Gamma-aminobutyric acid receptor-associated protein-like 1 / Q9H0R8* / GABA type A receptor associated protein like 1*ENSMUSG0000003016133
Q9DCD6 / Gabarap / Gamma-aminobutyric acid receptor-associated protein / O95166* / GABA type A receptor-associated protein*ENSMUSG0000001856730


Protein motifs (from Interpro)
Interpro ID Name
 IPR004241  Autophagy protein Atg8 ubiquitin-like
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IEA
 biological_processGO:0000422 autophagy of mitochondrion IEA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0006995 cellular response to nitrogen starvation IBA
 biological_processGO:0009267 cellular response to starvation IEA
 biological_processGO:0010040 response to iron(II) ion IEA
 biological_processGO:0010288 response to lead ion IEA
 biological_processGO:0016236 macroautophagy IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0034198 cellular response to amino acid starvation IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071280 cellular response to copper ion IEA
 biological_processGO:0097352 autophagosome maturation IEA
 cellular_componentGO:0000421 autophagosome membrane IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005776 autophagosome ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0015630 microtubule cytoskeleton ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0044754 autolysosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008017 microtubule binding ISO
 molecular_functionGO:0008429 phosphatidylethanolamine binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA


Pathways (from Reactome)
Pathway description
Macroautophagy
Pink/Parkin Mediated Mitophagy
Receptor Mediated Mitophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025040 Fundc1 / Q9DB70 / FUN14 domain-containing protein 1 / Q8IVP5* / FUN14 domain containing 1*  / complex / reaction
 ENSMUSG00000038160 Atg5 / Q99J83 / Autophagy protein 5 / Q9H1Y0* / autophagy related 5*  / reaction / complex
 ENSMUSG00000032905 Atg12 / Q9CQY1 / Ubiquitin-like protein ATG12 / O94817* / autophagy related 12*  / complex / reaction






 

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