ENSG00000247077


Homo sapiens

Features
Gene ID: ENSG00000247077
  
Biological name :PGAM5
  
Synonyms : PGAM5 / PGAM family member 5, mitochondrial serine/threonine protein phosphatase / Q96HS1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.33
Gene start: 132710819
Gene end: 132722734
  
Corresponding Affymetrix probe sets: 1553837_at (Human Genome U133 Plus 2.0 Array)   1555943_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000321503
Ensembl peptide - ENSP00000409537
Ensembl peptide - ENSP00000438465
Ensembl peptide - ENSP00000440372
NCBI entrez gene - 192111     See in Manteia.
OMIM - 614939
RefSeq - NM_001170543
RefSeq - NM_001170544
RefSeq - NM_138575
RefSeq Peptide - NP_001164014
RefSeq Peptide - NP_001164015
RefSeq Peptide - NP_612642
swissprot - Q96HS1
swissprot - F5GXG4
Ensembl - ENSG00000247077
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgam5ENSDARG00000035608Danio rerio
 PGAM5ENSGALG00000002137Gallus gallus
 Pgam5ENSMUSG00000029500Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0012501 programmed cell death IEA
 biological_processGO:0016236 macroautophagy TAS
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0070266 necroptotic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity TAS
 molecular_functionGO:0005096 GTPase activator activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0009400 obsolete signal transducer, downstream of receptor, with serine/threonine phosphatase activity IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IMP
 molecular_functionGO:0044877 protein-containing complex binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000069509 FUNDC1 / Q8IVP5 / FUN14 domain containing 1  / reaction






 

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