ENSG00000122257


Homo sapiens

Features
Gene ID: ENSG00000122257
  
Biological name :RBBP6
  
Synonyms : Q7Z6E9 / RB binding protein 6, ubiquitin ligase / RBBP6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p12.1
Gene start: 24537693
Gene end: 24572863
  
Corresponding Affymetrix probe sets: 1552329_at (Human Genome U133 Plus 2.0 Array)   205178_s_at (Human Genome U133 Plus 2.0 Array)   212781_at (Human Genome U133 Plus 2.0 Array)   212783_at (Human Genome U133 Plus 2.0 Array)   223802_s_at (Human Genome U133 Plus 2.0 Array)   227635_at (Human Genome U133 Plus 2.0 Array)   228814_at (Human Genome U133 Plus 2.0 Array)   232044_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000460821
Ensembl peptide - ENSP00000496720
Ensembl peptide - ENSP00000481477
Ensembl peptide - ENSP00000316291
Ensembl peptide - ENSP00000317872
Ensembl peptide - ENSP00000370427
Ensembl peptide - ENSP00000390537
Ensembl peptide - ENSP00000456750
Ensembl peptide - ENSP00000457716
NCBI entrez gene - 5930     See in Manteia.
OMIM - 600938
RefSeq - NM_006910
RefSeq - NM_018703
RefSeq - NM_032626
RefSeq Peptide - NP_116015
RefSeq Peptide - NP_008841
RefSeq Peptide - NP_061173
swissprot - Q7Z6E9
swissprot - H3BSK8
swissprot - H3BUN0
swissprot - I3L3Y2
swissprot - A0A087WY32
Ensembl - ENSG00000122257
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rbbp6ENSDARG00000037919Danio rerio
 RBBP6ENSGALG00000006043Gallus gallus
 Rbbp6ENSMUSG00000030779Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR001878  Zinc finger, CCHC-type
 IPR003613  U box domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR014891  DWNN domain
 IPR025829  Zinc knuckle CX2CX3GHX4C
 IPR033489  E3 ubiquitin-protein ligase RBBP6
 IPR036875  Zinc finger, CCHC-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006275 regulation of DNA replication IMP
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0048568 embryonic organ development IEA
 biological_processGO:0061053 somite development IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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