ENSG00000122674


Homo sapiens

Features
Gene ID: ENSG00000122674
  
Biological name :CCZ1
  
Synonyms : CCZ1 / CCZ1 homolog, vacuolar protein trafficking and biogenesis associated / P86791
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p22.1
Gene start: 5898725
Gene end: 5926550
  
Corresponding Affymetrix probe sets: 201973_s_at (Human Genome U133 Plus 2.0 Array)   201974_s_at (Human Genome U133 Plus 2.0 Array)   208310_s_at (Human Genome U133 Plus 2.0 Array)   215024_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000325681
Ensembl peptide - ENSP00000486988
NCBI entrez gene - 51622     See in Manteia.
RefSeq - NM_015622
RefSeq Peptide - NP_056437
swissprot - F8WD66
swissprot - P86791
Ensembl - ENSG00000122674
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccz1ENSDARG00000056559Danio rerio
 CCZ1ENSGALG00000003458Gallus gallus
 Ccz1ENSMUSG00000029617Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCZ1B / P86790 / CCZ1 homolog B, vacuolar protein trafficking and biogenesis associatedENSG00000146574100


Protein motifs (from Interpro)
Interpro ID Name
 IPR013176  Protein of unknown function DUF1712, fungi


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016192 vesicle-mediated transport IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016235 aggresome IDA
 cellular_componentGO:0031982 vesicle IBA
 cellular_componentGO:0035658 Mon1-Ccz1 complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000057608 GDI2 / P50395 / GDP dissociation inhibitor 2  / reaction
 ENSG00000203668 CHML / P26374 / CHM like, Rab escort protein 2  / reaction
 ENSG00000203879 GDI1 / P31150 / GDP dissociation inhibitor 1  / reaction
 ENSG00000164077 MON1A / Q86VX9 / MON1 homolog A, secretory trafficking associated  / complex
 ENSG00000188419 CHM / P24386 / CHM, Rab escort protein 1  / reaction
 ENSG00000075785 RAB7A / P51149 / RAB7A, member RAS oncogene family  / reaction






 

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