ENSG00000123496


Homo sapiens

Features
Gene ID: ENSG00000123496
  
Biological name :IL13RA2
  
Synonyms : IL13RA2 / interleukin 13 receptor subunit alpha 2 / Q14627
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q23
Gene start: 115003975
Gene end: 115019977
  
Corresponding Affymetrix probe sets: 206172_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361004
Ensembl peptide - ENSP00000243213
NCBI entrez gene - 3598     See in Manteia.
OMIM - 300130
RefSeq - NM_000640
RefSeq Peptide - NP_000631
swissprot - Q14627
Ensembl - ENSG00000123496
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il13ra2ENSDARG00000039436Danio rerio
 IL13RA2ENSGALG00000020316Gallus gallus
 O88786ENSMUSG00000031289Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IL5RA / Q01344 / interleukin 5 receptor subunit alphaENSG0000009118125
P78552 / IL13RA1 / interleukin 13 receptor subunit alpha 1ENSG0000013172422


Protein motifs (from Interpro)
Interpro ID Name
 IPR003532  Short hematopoietin receptor, family 2, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015321  Type I cytokine receptor, cytokine-binding domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002638 negative regulation of immunoglobulin production IEA
 biological_processGO:0016064 immunoglobulin mediated immune response IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0043305 negative regulation of mast cell degranulation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity TAS
 molecular_functionGO:0004896 cytokine receptor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169194 IL13 / P35225 / interleukin 13  / reaction / complex






 

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