ENSG00000131724


Homo sapiens

Features
Gene ID: ENSG00000131724
  
Biological name :IL13RA1
  
Synonyms : IL13RA1 / interleukin 13 receptor subunit alpha 1 / P78552
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q24
Gene start: 118727572
Gene end: 118794539
  
Corresponding Affymetrix probe sets: 201887_at (Human Genome U133 Plus 2.0 Array)   201888_s_at (Human Genome U133 Plus 2.0 Array)   210904_s_at (Human Genome U133 Plus 2.0 Array)   211612_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360705
Ensembl peptide - ENSP00000360730
NCBI entrez gene - 3597     See in Manteia.
OMIM - 300119
RefSeq - XM_017029507
RefSeq - NM_001560
RefSeq - XM_011531336
RefSeq Peptide - NP_001551
swissprot - P78552
Ensembl - ENSG00000131724
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il13ra2ENSDARG00000039436Danio rerio
 IL13RA1ENSGALG00000044480Gallus gallus
 O09030ENSMUSG00000017057Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q14627 / IL13RA2 / interleukin 13 receptor subunit alpha 2ENSG0000012349620
IL5RA / Q01344 / interleukin 5 receptor subunit alphaENSG0000009118119


Protein motifs (from Interpro)
Interpro ID Name
 IPR003532  Short hematopoietin receptor, family 2, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015321  Type I cytokine receptor, cytokine-binding domain
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005898 interleukin-13 receptor complex TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Interleukin-4 and Interleukin-13 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000077238 IL4R / P24394 / interleukin 4 receptor  / reaction / complex
 ENSG00000168610 STAT3 / P40763 / signal transducer and activator of transcription 3  / complex / reaction
 ENSG00000166888 STAT6 / P42226 / signal transducer and activator of transcription 6  / complex / reaction
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / complex
 ENSG00000115415 STAT1 / P42224 / signal transducer and activator of transcription 1  / complex / reaction
 ENSG00000171150 SOCS5 / O75159 / suppressor of cytokine signaling 5  / complex / reaction
 ENSG00000169194 IL13 / P35225 / interleukin 13  / reaction / complex
 ENSG00000113520 IL4 / P05112 / interleukin 4  / reaction / complex
 ENSG00000105397 TYK2 / P29597 / tyrosine kinase 2  / complex / reaction
 ENSG00000096968 JAK2 / O60674 / Janus kinase 2  / complex / reaction






 

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