ENSG00000123576


Homo sapiens

Features
Gene ID: ENSG00000123576
  
Biological name :ESX1
  
Synonyms : ESX1 / ESX homeobox 1 / Q8N693
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q22.2
Gene start: 104250038
Gene end: 104254933
  
Corresponding Affymetrix probe sets: 1552445_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361669
NCBI entrez gene - 80712     See in Manteia.
OMIM - 300154
RefSeq - NM_153448
RefSeq Peptide - NP_703149
swissprot - Q8N693
Ensembl - ENSG00000123576
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Esx1ENSMUSG00000023443Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OTP / Q5XKR4 / orthopedia homeoboxENSG0000017154017
SHOX2 / O60902 / short stature homeobox 2ENSG0000016877917
SHOX / O15266 / short stature homeoboxENSG0000018596017
P0C7M4 / RHOXF2B / Rhox homeobox family member 2BENSG0000020398916
Q9BQY4 / RHOXF2 / Rhox homeobox family member 2ENSG0000013172115
Q8NHV9 / RHOXF1 / Rhox homeobox family member 1ENSG0000010188312


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR013847  POU domain
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0051726 regulation of cell cycle IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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