ENSG00000171540


Homo sapiens

Features
Gene ID: ENSG00000171540
  
Biological name :OTP
  
Synonyms : orthopedia homeobox / OTP / Q5XKR4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q14.1
Gene start: 77628712
Gene end: 77639688
  
Corresponding Affymetrix probe sets: 223835_x_at (Human Genome U133 Plus 2.0 Array)   231488_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302814
NCBI entrez gene - 23440     See in Manteia.
OMIM - 604529
RefSeq - NM_032109
RefSeq Peptide - NP_115485
swissprot - Q5XKR4
Ensembl - ENSG00000171540
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 otpaENSDARG00000014201Danio rerio
 otpbENSDARG00000058379Danio rerio
 OTPENSGALG00000026744Gallus gallus
 OtpENSMUSG00000021685Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SHOX2 / O60902 / short stature homeobox 2ENSG0000016877923
SHOX / O15266 / short stature homeoboxENSG0000018596021
ESX1 / Q8N693 / ESX homeobox 1ENSG0000012357621
Q9BQY4 / RHOXF2 / Rhox homeobox family member 2ENSG0000013172118
P0C7M4 / RHOXF2B / Rhox homeobox family member 2BENSG0000020398917
Q8NHV9 / RHOXF1 / Rhox homeobox family member 1ENSG0000010188313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR003654  OAR domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002052 positive regulation of neuroblast proliferation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0021879 forebrain neuron differentiation IEA
 biological_processGO:0021979 hypothalamus cell differentiation IEA
 biological_processGO:0021985 neurohypophysis development IEA
 biological_processGO:0030154 cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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