ENSG00000123933


Homo sapiens

Features
Gene ID: ENSG00000123933
  
Biological name :MXD4
  
Synonyms : MAX dimerization protein 4 / MXD4 / Q14582
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.3
Gene start: 2247432
Gene end: 2262294
  
Corresponding Affymetrix probe sets: 210778_s_at (Human Genome U133 Plus 2.0 Array)   212346_s_at (Human Genome U133 Plus 2.0 Array)   212347_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000422660
Ensembl peptide - ENSP00000337889
Ensembl peptide - ENSP00000421209
NCBI entrez gene - 10608     See in Manteia.
RefSeq - XM_017007656
RefSeq - NM_006454
RefSeq Peptide - NP_006445
swissprot - D6RGV1
swissprot - Q14582
swissprot - H0Y8Z5
Ensembl - ENSG00000123933
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mxd4ENSDARG00000054031Danio rerio
 MXD4ENSGALG00000015688Gallus gallus
 Mxd4ENSMUSG00000037235Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MXI1 / P50539 / MAX interactor 1, dimerization proteinENSG0000011995040
MXD1 / Q05195 / MAX dimerization protein 1ENSG0000005972837
MXD3 / Q9BW11 / MAX dimerization protein 3ENSG0000021334730


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II TAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008285 negative regulation of cell proliferation TAS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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