ENSG00000213347


Homo sapiens

Features
Gene ID: ENSG00000213347
  
Biological name :MXD3
  
Synonyms : MAX dimerization protein 3 / MXD3 / Q9BW11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q35.3
Gene start: 177301461
Gene end: 177312757
  
Corresponding Affymetrix probe sets: 1555311_at (Human Genome U133 Plus 2.0 Array)   221250_s_at (Human Genome U133 Plus 2.0 Array)   225251_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000425029
Ensembl peptide - ENSP00000401867
Ensembl peptide - ENSP00000427104
Ensembl peptide - ENSP00000416921
Ensembl peptide - ENSP00000421463
Ensembl peptide - ENSP00000389716
NCBI entrez gene - 83463     See in Manteia.
OMIM - 609450
RefSeq - NM_031300
RefSeq - NM_001142935
RefSeq Peptide - NP_001136407
RefSeq Peptide - NP_112590
swissprot - Q9BW11
swissprot - D6RD21
swissprot - A0A024R7S0
swissprot - D6RED4
Ensembl - ENSG00000213347
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mxd3ENSDARG00000098350Danio rerio
 MXD3ENSGALG00000046263Gallus gallus
 Mxd3ENSMUSG00000021485Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MXI1 / P50539 / MAX interactor 1, dimerization proteinENSG0000011995041
MXD1 / Q05195 / MAX dimerization protein 1ENSG0000005972841
MXD4 / Q14582 / MAX dimerization protein 4ENSG0000012393330


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR036638  Helix-loop-helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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