ENSG00000124226


Homo sapiens

Features
Gene ID: ENSG00000124226
  
Biological name :RNF114
  
Synonyms : Q9Y508 / ring finger protein 114 / RNF114
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.13
Gene start: 49936336
Gene end: 49953892
  
Corresponding Affymetrix probe sets: 200867_at (Human Genome U133 Plus 2.0 Array)   200868_s_at (Human Genome U133 Plus 2.0 Array)   211678_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000244061
Ensembl peptide - ENSP00000485575
Ensembl peptide - ENSP00000485317
Ensembl peptide - ENSP00000485239
Ensembl peptide - ENSP00000485203
Ensembl peptide - ENSP00000485136
NCBI entrez gene - 55905     See in Manteia.
OMIM - 612451
RefSeq - NM_018683
RefSeq Peptide - NP_061153
swissprot - A0A096LNT1
swissprot - A0A096LNN8
swissprot - A0A096LPF9
swissprot - Q9Y508
swissprot - A0A096LP02
swissprot - A0A096LNV3
Ensembl - ENSG00000124226
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf114ENSDARG00000009886Danio rerio
 RNF114ENSGALG00000008021Gallus gallus
 Q9ET26ENSMUSG00000006418Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96A37 / RNF166 / ring finger protein 166ENSG0000015871743
Q8WVD3 / RNF138 / ring finger protein 138ENSG0000013475830
Q96EQ8 / RNF125 / ring finger protein 125ENSG0000010169528


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR008598  Drought induced 19 protein type, zinc-binding domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR034734  Zinc finger C2HC RNF-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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