ENSG00000134758


Homo sapiens

Features
Gene ID: ENSG00000134758
  
Biological name :RNF138
  
Synonyms : Q8WVD3 / ring finger protein 138 / RNF138
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q12.1
Gene start: 32091855
Gene end: 32131561
  
Corresponding Affymetrix probe sets: 218738_s_at (Human Genome U133 Plus 2.0 Array)   239143_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463153
Ensembl peptide - ENSP00000462498
Ensembl peptide - ENSP00000463659
Ensembl peptide - ENSP00000257190
Ensembl peptide - ENSP00000261593
Ensembl peptide - ENSP00000462165
NCBI entrez gene - 51444     See in Manteia.
OMIM - 616319
RefSeq - XM_005258286
RefSeq - NM_001191324
RefSeq - NM_016271
RefSeq - NM_198128
RefSeq - XM_005258285
RefSeq Peptide - NP_937761
RefSeq Peptide - NP_001178253
RefSeq Peptide - NP_057355
swissprot - J3QKM8
swissprot - J3QLQ3
swissprot - J3KRU4
swissprot - J3KSI2
swissprot - Q8WVD3
swissprot - A0A140VJT9
Ensembl - ENSG00000134758
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RNF138ENSGALG00000015163Gallus gallus
 Q9CQE0ENSMUSG00000024317Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96A37 / RNF166 / ring finger protein 166ENSG0000015871729
Q9Y508 / RNF114 / ring finger protein 114ENSG0000012422628
Q96EQ8 / RNF125 / ring finger protein 125ENSG0000010169525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR004181  Zinc finger, MIZ-type
 IPR008598  Drought induced 19 protein type, zinc-binding domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR034734  Zinc finger C2HC RNF-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0000724 double-strand break repair via homologous recombination IMP
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0010792 DNA double-strand break processing involved in repair via single-strand annealing IMP
 biological_processGO:0016055 Wnt signaling pathway IEA
 biological_processGO:0016567 protein ubiquitination IMP
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0035861 site of double-strand break IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003697 single-stranded DNA binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IMP


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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