ENSG00000124233


Homo sapiens

Features
Gene ID: ENSG00000124233
  
Biological name :SEMG1
  
Synonyms : P04279 / semenogelin I / SEMG1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q13.12
Gene start: 45206997
Gene end: 45209772
  
Corresponding Affymetrix probe sets: 206442_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361867
NCBI entrez gene - 6406     See in Manteia.
OMIM - 182140
RefSeq - NM_003007
RefSeq Peptide - NP_002998
swissprot - P04279
Ensembl - ENSG00000124233
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SEMG2 / Q02383 / semenogelin IIENSG0000012415778


Protein motifs (from Interpro)
Interpro ID Name
 IPR008836  Semenogelin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007320 insemination TAS
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0019731 antibacterial humoral response IDA
 biological_processGO:0031640 killing of cells of other organism IDA
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0050817 coagulation IDA
 biological_processGO:0051291 protein heterooligomerization IDA
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IDA
 biological_processGO:0090281 negative regulation of calcium ion import IDA
 biological_processGO:1900005 positive regulation of serine-type endopeptidase activity IMP
 biological_processGO:1901318 negative regulation of flagellated sperm motility IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IMP


Pathways (from Reactome)
Pathway description
Antimicrobial peptides
Amyloid fiber formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000012223 LTF / P02788 / lactotransferrin  / complex
 ENSG00000101448 EPPIN / O95925 / epididymal peptidase inhibitor  / complex
 ENSG00000120885 CLU / P10909 / clusterin  / complex
 ENSG00000124233 SEMG1 / P04279 / semenogelin I  / -






 

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