ENSG00000124469


Homo sapiens

Features
Gene ID: ENSG00000124469
  
Biological name :CEACAM8
  
Synonyms : carcinoembryonic antigen related cell adhesion molecule 8 / CEACAM8 / P31997
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.2
Gene start: 42580241
Gene end: 42595055
  
Corresponding Affymetrix probe sets: 206676_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000244336
Ensembl peptide - ENSP00000472166
NCBI entrez gene - 1088     See in Manteia.
OMIM - 615747
RefSeq - XM_017026198
RefSeq - NM_001816
RefSeq - XM_011526341
RefSeq - XM_011526342
RefSeq - XM_017026195
RefSeq - XM_017026196
RefSeq - XM_011526340
RefSeq Peptide - NP_001807
swissprot - P31997
swissprot - Q0Z7S6
swissprot - M0R1X3
Ensembl - ENSG00000124469
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-250k15.9ENSDARG00000095134Danio rerio
 Ceacam10ENSMUSG00000054169Mus musculus
 Ceacam11ENSMUSG00000030368Mus musculus
 Ceacam12ENSMUSG00000030366Mus musculus
 Ceacam13ENSMUSG00000057195Mus musculus
 Ceacam14ENSMUSG00000023185Mus musculus
 Ceacam3ENSMUSG00000053228Mus musculus
 P31809ENSMUSG00000074272Mus musculus
 Psg16ENSMUSG00000066760Mus musculus
 Psg17ENSMUSG00000004540Mus musculus
 Psg18ENSMUSG00000003505Mus musculus
 Psg19ENSMUSG00000004542Mus musculus
 Psg20ENSMUSG00000063305Mus musculus
 Psg21ENSMUSG00000070796Mus musculus
 Psg22ENSMUSG00000044903Mus musculus
 Psg23ENSMUSG00000074359Mus musculus
 Psg25ENSMUSG00000070798Mus musculus
 Psg26ENSMUSG00000070799Mus musculus
 Psg27ENSMUSG00000070797Mus musculus
 Psg28ENSMUSG00000030373Mus musculus
 Psg29ENSMUSG00000023159Mus musculus
 Q3UKK2ENSMUSG00000008789Mus musculus
 Q925P2ENSMUSG00000054385Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P40199 / CEACAM6 / carcinoembryonic antigen related cell adhesion molecule 6ENSG0000008654878
P13688 / CEACAM1 / carcinoembryonic antigen related cell adhesion molecule 1ENSG0000007938576
P06731 / CEACAM5 / carcinoembryonic antigen related cell adhesion molecule 5ENSG0000010538875
PSG8 / Q9UQ74 / pregnancy specific beta-1-glycoprotein 8ENSG0000012446758
PSG1 / P11464 / pregnancy specific beta-1-glycoprotein 1ENSG0000023192456
PSG3 / Q16557 / pregnancy specific beta-1-glycoprotein 3ENSG0000022182656
PSG9 / Q00887 / pregnancy specific beta-1-glycoprotein 9ENSG0000018366855
PSG2 / P11465 / pregnancy specific beta-1-glycoprotein 2ENSG0000024222155
PSG6 / Q00889 / pregnancy specific beta-1-glycoprotein 6ENSG0000017084855
PSG4 / Q00888 / pregnancy specific beta-1-glycoprotein 4ENSG0000024313755
PSG11 / Q9UQ72 / pregnancy specific beta-1-glycoprotein 11ENSG0000024313054
Q14002 / CEACAM7 / carcinoembryonic antigen related cell adhesion molecule 7ENSG0000000730652
PSG5 / Q15238 / pregnancy specific beta-1-glycoprotein 5ENSG0000020494138
PSG7 / pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)ENSG0000022187836
Q3KPI0 / CEACAM21 / carcinoembryonic antigen related cell adhesion molecule 21ENSG0000000712934
P40198 / CEACAM3 / carcinoembryonic antigen related cell adhesion molecule 3ENSG0000017095632
AC243967.1ENSG0000026788132
Q2WEN9 / CEACAM16 / carcinoembryonic antigen related cell adhesion molecule 16ENSG0000021389227
CEACAM20 / carcinoembryonic antigen related cell adhesion molecule 20ENSG0000027377726
A8MTB9 / CEACAM18 / carcinoembryonic antigen related cell adhesion molecule 18ENSG0000021382225


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006955 immune response TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Fibronectin matrix formation
Cell surface interactions at the vascular wall
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000086548 P40199 / CEACAM6 / carcinoembryonic antigen related cell adhesion molecule 6  / reaction / complex
 ENSG00000124469 P31997 / CEACAM8 / carcinoembryonic antigen related cell adhesion molecule 8  / complex / reaction
 ENSG00000079385 P13688 / CEACAM1 / carcinoembryonic antigen related cell adhesion molecule 1  / reaction / complex






 

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