ENSG00000124588


Homo sapiens

Features
Gene ID: ENSG00000124588
  
Biological name :NQO2
  
Synonyms : NQO2 / N-ribosyldihydronicotinamide:quinone reductase 2 / P16083
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p25.2
Gene start: 2987987
Gene end: 3028869
  
Corresponding Affymetrix probe sets: 203814_s_at (Human Genome U133 Plus 2.0 Array)   237870_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406951
Ensembl peptide - ENSP00000380829
Ensembl peptide - ENSP00000475864
Ensembl peptide - ENSP00000337773
Ensembl peptide - ENSP00000369795
Ensembl peptide - ENSP00000369806
Ensembl peptide - ENSP00000369821
Ensembl peptide - ENSP00000369822
Ensembl peptide - ENSP00000369839
NCBI entrez gene - 4835     See in Manteia.
OMIM - 160998
RefSeq - NM_000904
RefSeq - NM_001290221
RefSeq - NM_001290222
RefSeq - NM_001318940
RefSeq Peptide - NP_000895
RefSeq Peptide - NP_001277150
RefSeq Peptide - NP_001277151
RefSeq Peptide - NP_001305869
swissprot - U3KQG7
swissprot - Q5TD07
swissprot - P16083
swissprot - A2A2U4
swissprot - Q5TD05
Ensembl - ENSG00000124588
  
Related genetic diseases (OMIM): 114480 - {?Breast cancer susceptibility}, 114480
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NQO2ENSGALG00000025747Gallus gallus
 Nqo2ENSMUSG00000046949Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NQO1 / P15559 / NAD(P)H quinone dehydrogenase 1ENSG0000018101947


Protein motifs (from Interpro)
Interpro ID Name
 IPR003680  Flavodoxin-like fold
 IPR029039  Flavoprotein-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006805 xenobiotic metabolic process TAS
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0055114 oxidation-reduction process IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001512 dihydronicotinamide riboside quinone reductase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0009055 electron transfer activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IDA
 molecular_functionGO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors IDA
 molecular_functionGO:0031404 chloride ion binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0071949 FAD binding IDA
 molecular_functionGO:1904408 melatonin binding IDA
 molecular_functionGO:1905594 resveratrol binding IDA


Pathways (from Reactome)
Pathway description
Phase I - Functionalization of compounds


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000124588 NQO2 / P16083 / N-ribosyldihydronicotinamide:quinone reductase 2  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr