ENSG00000125733


Homo sapiens

Features
Gene ID: ENSG00000125733
  
Biological name :TRIP10
  
Synonyms : Q15642 / thyroid hormone receptor interactor 10 / TRIP10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 6737925
Gene end: 6751526
  
Corresponding Affymetrix probe sets: 202734_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472580
Ensembl peptide - ENSP00000471056
Ensembl peptide - ENSP00000471203
Ensembl peptide - ENSP00000320117
Ensembl peptide - ENSP00000320493
Ensembl peptide - ENSP00000469360
NCBI entrez gene - 9322     See in Manteia.
OMIM - 604504
RefSeq - XM_006722940
RefSeq - NM_001288962
RefSeq - NM_001288963
RefSeq - NM_004240
RefSeq - XM_005259683
RefSeq Peptide - NP_001275892
RefSeq Peptide - NP_004231
RefSeq Peptide - NP_001275891
swissprot - Q15642
swissprot - M0R070
swissprot - W4VSQ9
swissprot - M0R0F9
swissprot - M0R2H7
Ensembl - ENSG00000125733
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trip10aENSDARG00000005679Danio rerio
 trip10bENSDARG00000100788Danio rerio
 Q8CJ53ENSMUSG00000019487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FNBP1L / Q5T0N5 / formin binding protein 1 likeENSG0000013794252
FNBP1 / Q96RU3 / formin binding protein 1ENSG0000018723951


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR028498  Cdc42-interacting protein 4
 IPR031160  F-BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007154 cell communication NAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0051056 regulation of small GTPase mediated signal transduction TAS
 biological_processGO:0061024 membrane organization TAS
 cellular_componentGO:0001891 phagocytic cup IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm NAS
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005096 GTPase activator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Rho GTPase cycle
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125733 Q15642 / TRIP10 / thyroid hormone receptor interactor 10  / complex






 

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