ENSG00000137942


Homo sapiens

Features
Gene ID: ENSG00000137942
  
Biological name :FNBP1L
  
Synonyms : FNBP1L / formin binding protein 1 like / Q5T0N5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p22.1
Gene start: 93448131
Gene end: 93554661
  
Corresponding Affymetrix probe sets: 215017_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000260506
Ensembl peptide - ENSP00000359275
Ensembl peptide - ENSP00000397451
Ensembl peptide - ENSP00000473921
Ensembl peptide - ENSP00000271234
NCBI entrez gene - 54874     See in Manteia.
OMIM - 608848
RefSeq - XM_017001533
RefSeq - NM_001024948
RefSeq - NM_001164473
RefSeq - NM_017737
RefSeq - XM_011541625
RefSeq Peptide - NP_001157945
RefSeq Peptide - NP_060207
RefSeq Peptide - NP_001020119
swissprot - Q5T0N5
swissprot - S4R347
swissprot - A0A075B6Q2
Ensembl - ENSG00000137942
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fnbp1lENSDARG00000020131Danio rerio
 FNBP1LENSGALG00000005850Gallus gallus
 Fnbp1lENSMUSG00000039735Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FNBP1 / Q96RU3 / formin binding protein 1ENSG0000018723956
Q15642 / TRIP10 / thyroid hormone receptor interactor 10ENSG0000012573351


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR030116  Formin-binding protein 1-like
 IPR031160  F-BAR domain
 IPR035493  FNBP1L, SH3 domain
 IPR035494  FNBP1L, F-BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006900 vesicle budding from membrane IDA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0010324 membrane invagination IDA
 biological_processGO:0016050 vesicle organization IDA
 biological_processGO:0030050 vesicle transport along actin filament IDA
 biological_processGO:0051491 positive regulation of filopodium assembly IDA
 biological_processGO:0060271 cilium assembly IMP
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0072583 clathrin-dependent endocytosis IDA
 biological_processGO:0097320 plasma membrane tubulation IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051020 GTPase binding IPI


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137942 FNBP1L / Q5T0N5 / formin binding protein 1 like  / complex






 

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