ENSMUSG00000039735


Mus musculus

Features
Gene ID: ENSMUSG00000039735
  
Biological name :Fnbp1l
  
Synonyms : Fnbp1l / formin binding protein 1 like
  
Possible biological names infered from orthology : Q5T0N5
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: G1
Gene start: 122538719
Gene end: 122619715
  
Corresponding Affymetrix probe sets: 10501860 (MoGene1.0st)   1434339_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124439
Ensembl peptide - ENSMUSP00000143237
Ensembl peptide - ENSMUSP00000124947
NCBI entrez gene - 214459     See in Manteia.
MGI - MGI:1925642
RefSeq - NM_153118
RefSeq - NM_001114665
RefSeq Peptide - NP_694758
RefSeq Peptide - NP_001108137
swissprot - E9PUI5
swissprot - E9PUK3
swissprot - A0A0G2JFM9
Ensembl - ENSMUSG00000039735
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fnbp1lENSDARG00000020131Danio rerio
 FNBP1LENSGALG00000005850Gallus gallus
 FNBP1LENSG00000137942Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fnbp1 / Q80TY0 / Mus musculus formin binding protein 1 (Fnbp1), transcript variant 6, mRNA. / Q96RU3* / formin binding protein 1*ENSMUSG0000007541554
Q8CJ53 / Trip10 / thyroid hormone receptor interactor 10 / Q15642*ENSMUSG0000001948748


Protein motifs (from Interpro)
Interpro ID Name
 IPR001060  FCH domain
 IPR001452  SH3 domain
 IPR027267  AH/BAR domain superfamily
 IPR030116  Formin-binding protein 1-like
 IPR031160  F-BAR domain
 IPR035493  FNBP1L, SH3 domain
 IPR035494  FNBP1L, F-BAR domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006900 vesicle budding from membrane IEA
 biological_processGO:0010324 membrane invagination IEA
 biological_processGO:0016050 vesicle organization IEA
 biological_processGO:0030050 vesicle transport along actin filament IEA
 biological_processGO:0051491 positive regulation of filopodium assembly IEA
 biological_processGO:0060271 cilium assembly IEA
 biological_processGO:0072583 clathrin-dependent endocytosis IEA
 biological_processGO:0097320 plasma membrane tubulation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051020 GTPase binding IEA


Pathways (from Reactome)
Pathway description
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/J

 MP:0010123 increased bone mineral content "elevation in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/J

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
Show

Allelic Composition: Fgf9tm1b(KOMP)Wtsi/Fgf9tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Fgf9tm1b(KOMP)Wtsi/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000039735 Fnbp1l / formin binding protein 1 like / Q5T0N5*  / complex






 

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