ENSG00000126602


Homo sapiens

Features
Gene ID: ENSG00000126602
  
Biological name :TRAP1
  
Synonyms : Q12931 / TNF receptor associated protein 1 / TRAP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: p13.3
Gene start: 3651639
Gene end: 3717597
  
Corresponding Affymetrix probe sets: 201391_at (Human Genome U133 Plus 2.0 Array)   239622_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000461354
Ensembl peptide - ENSP00000460545
Ensembl peptide - ENSP00000461618
Ensembl peptide - ENSP00000246957
Ensembl peptide - ENSP00000442070
Ensembl peptide - ENSP00000458166
Ensembl peptide - ENSP00000458244
Ensembl peptide - ENSP00000459354
Ensembl peptide - ENSP00000459385
Ensembl peptide - ENSP00000459585
NCBI entrez gene - 10131     See in Manteia.
OMIM - 606219
RefSeq - XM_017022851
RefSeq - NM_001272049
RefSeq - NM_016292
RefSeq - XM_011522345
RefSeq Peptide - NP_057376
RefSeq Peptide - NP_001258978
swissprot - I3L3L4
swissprot - I3L4L7
swissprot - Q12931
swissprot - A0A140VJY2
swissprot - I3L0K7
swissprot - I3L0P6
swissprot - I3L253
swissprot - I3L239
swissprot - I3L2D5
Ensembl - ENSG00000126602
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 trap1ENSDARG00000024317Danio rerio
 TRAP1ENSGALG00000039951Gallus gallus
 Trap1ENSMUSG00000005981Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P14625 / HSP90B1 / heat shock protein 90 beta family member 1ENSG0000016659831
P07900 / HSP90AA1 / heat shock protein 90 alpha family class A member 1ENSG0000008082431
P08238 / HSP90AB1 / heat shock protein 90 alpha family class B member 1ENSG0000009638430


Protein motifs (from Interpro)
Interpro ID Name
 IPR001404  Heat shock protein Hsp90 family
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR020575  Heat shock protein Hsp90, N-terminal
 IPR036890  Histidine kinase/HSP90-like ATPase superfamily
 IPR037196  HSP90, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0009386 translational attenuation IMP
 biological_processGO:0061077 chaperone-mediated protein folding TAS
 biological_processGO:1901856 negative regulation of cellular respiration IMP
 biological_processGO:1903427 negative regulation of reactive oxygen species biosynthetic process TAS
 biological_processGO:1903751 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 cellular_componentGO:0005758 mitochondrial intermembrane space ISS
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005164 tumor necrosis factor receptor binding NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0051082 unfolded protein binding IEA


Pathways (from Reactome)
Pathway description
Respiratory electron transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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