ENSG00000128016


Homo sapiens

Features
Gene ID: ENSG00000128016
  
Biological name :ZFP36
  
Synonyms : ZFP36 / ZFP36 ring finger protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 39406813
Gene end: 39409412
  
Corresponding Affymetrix probe sets: 201531_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000470200
Ensembl peptide - ENSP00000469647
Ensembl peptide - ENSP00000471239
Ensembl peptide - ENSP00000472329
NCBI entrez gene - 7538     See in Manteia.
OMIM - 190700
RefSeq - NM_003407
RefSeq Peptide - NP_003398
swissprot - M0R0H3
swissprot - M0R252
swissprot - M0QZ04
swissprot - M0QY76
Ensembl - ENSG00000128016
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:162730ENSDARG00000103720Danio rerio
 Zfp36ENSMUSG00000044786Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q07352 / ZFP36L1 / ZFP36 ring finger protein like 1ENSG0000018565034
P47974 / ZFP36L2 / ZFP36 ring finger protein like 2ENSG0000015251834


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0035278 miRNA mediated inhibition of translation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0038066 p38MAPK cascade IEA
 biological_processGO:0043488 regulation of mRNA stability IEA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEA
 biological_processGO:0045085 negative regulation of interleukin-2 biosynthetic process IEA
 biological_processGO:0045600 positive regulation of fat cell differentiation IEA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050779 RNA destabilization IEA
 biological_processGO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening IEA
 biological_processGO:0061014 positive regulation of mRNA catabolic process IEA
 biological_processGO:0061158 3"-UTR-mediated mRNA destabilization IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:1904246 negative regulation of polynucleotide adenylyltransferase activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0030014 CCR4-NOT complex IEA
 cellular_componentGO:1990904 ribonucleoprotein complex IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017091 AU-rich element binding IEA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070063 RNA polymerase binding IEA
 molecular_functionGO:0071889 14-3-3 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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