ENSG00000152518


Homo sapiens

Features
Gene ID: ENSG00000152518
  
Biological name :ZFP36L2
  
Synonyms : P47974 / ZFP36L2 / ZFP36 ring finger protein like 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p21
Gene start: 43222402
Gene end: 43226609
  
Corresponding Affymetrix probe sets: 201367_s_at (Human Genome U133 Plus 2.0 Array)   201368_at (Human Genome U133 Plus 2.0 Array)   201369_s_at (Human Genome U133 Plus 2.0 Array)   227681_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000282388
NCBI entrez gene - 678     See in Manteia.
OMIM - 612053
RefSeq - NM_006887
RefSeq Peptide - NP_008818
swissprot - P47974
Ensembl - ENSG00000152518
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zfp36l2ENSDARG00000021806Danio rerio
 ZFP36L2ENSGALG00000033129Gallus gallus
 P23949ENSMUSG00000045817Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q07352 / ZFP36L1 / ZFP36 ring finger protein like 1ENSG0000018565038
ZFP36 / ZFP36 ring finger proteinENSG0000012801623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000571  Zinc finger, CCCH-type
 IPR007635  Tis11B-like protein, N-terminal
 IPR036855  Zinc finger, CCCH-type superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006402 mRNA catabolic process IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009611 response to wounding IDA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0033077 T cell differentiation in thymus IEA
 biological_processGO:0035019 somatic stem cell population maintenance IEA
 biological_processGO:0043488 regulation of mRNA stability IEA
 biological_processGO:0044344 cellular response to fibroblast growth factor stimulus IEA
 biological_processGO:0045577 regulation of B cell differentiation IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0048103 somatic stem cell division IEA
 biological_processGO:0060216 definitive hemopoiesis IEA
 biological_processGO:0061158 3"-UTR-mediated mRNA destabilization IEA
 biological_processGO:0070371 ERK1 and ERK2 cascade IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus IDA
 biological_processGO:0071385 cellular response to glucocorticoid stimulus IDA
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IDA
 biological_processGO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus IDA
 biological_processGO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay IEA
 biological_processGO:1901991 negative regulation of mitotic cell cycle phase transition IEA
 biological_processGO:2000737 negative regulation of stem cell differentiation IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017091 AU-rich element binding IDA
 molecular_functionGO:0035925 mRNA 3"-UTR AU-rich region binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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