ENSG00000128218


Homo sapiens

Features
Gene ID: ENSG00000128218
  
Biological name :VPREB3
  
Synonyms : Q9UKI3 / VPREB3 / V-set pre-B cell surrogate light chain 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q11.23
Gene start: 23752743
Gene end: 23754468
  
Corresponding Affymetrix probe sets: 220068_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000248948
Ensembl peptide - ENSP00000381483
NCBI entrez gene - 29802     See in Manteia.
OMIM - 605017
RefSeq - NM_013378
RefSeq Peptide - NP_037510
swissprot - A8MX21
swissprot - Q9UKI3
Ensembl - ENSG00000128218
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VPREB3ENSGALG00000021136Gallus gallus
 Vpreb3ENSMUSG00000000903Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IGLV5-45 / A0A087WSX0 / immunoglobulin lambda variable 5-45ENSG0000021165042
P12018 / VPREB1 / V-set pre-B cell surrogate light chain 1ENSG0000016957541
IGLV5-37 / A0A075B6J1 / immunoglobulin lambda variable 5-37ENSG0000021165441
IGLV11-55 / immunoglobulin lambda variable 11-55 (non-functional)ENSG0000021164139
IGLV5-52 / A0A0A0MRZ9 / immunoglobulin lambda variable 5-52ENSG0000021164339
IGLV5-48 / immunoglobulin lambda variable 5-48 (non-functional)ENSG0000021164737
IGLV4-69 / A0A075B6H9 / immunoglobulin lambda variable 4-69ENSG0000021163734
IGLV9-49 / A0A0B4J1Y8 / immunoglobulin lambda variable 9-49ENSG0000022335034
IGLV4-60 / A0A075B6I1 / immunoglobulin lambda variable 4-60ENSG0000021163933
IGLV4-3 / A0A075B6K6 / immunoglobulin lambda variable 4-3ENSG0000021167230


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002377 immunoglobulin production IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005783 endoplasmic reticulum NAS


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000128218 Q9UKI3 / VPREB3 / V-set pre-B cell surrogate light chain 3  / reaction / complex
 ENSG00000211899 IGHM / P01871 / immunoglobulin heavy constant mu  / reaction / complex
 ENSG00000128322 IGLL1 / P15814 / immunoglobulin lambda like polypeptide 1  / complex / reaction
 ENSG00000169575 P12018 / VPREB1 / V-set pre-B cell surrogate light chain 1  / complex / reaction






 

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