ENSG00000169575


Homo sapiens

Features
Gene ID: ENSG00000169575
  
Biological name :VPREB1
  
Synonyms : P12018 / VPREB1 / V-set pre-B cell surrogate light chain 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q11.22
Gene start: 22244675
Gene end: 22245515
  
Corresponding Affymetrix probe sets: 221349_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304590
Ensembl peptide - ENSP00000385361
NCBI entrez gene - 7441     See in Manteia.
OMIM - 605141
RefSeq - NM_001303509
RefSeq - NM_007128
RefSeq Peptide - NP_001290438
RefSeq Peptide - NP_009059
swissprot - P12018
swissprot - F8W8C9
Ensembl - ENSG00000169575
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P13372ENSMUSG00000059305Mus musculus
 P13373ENSMUSG00000059280Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IGLV5-37 / A0A075B6J1 / immunoglobulin lambda variable 5-37ENSG0000021165448
IGLV5-45 / A0A087WSX0 / immunoglobulin lambda variable 5-45ENSG0000021165045
IGLV5-52 / A0A0A0MRZ9 / immunoglobulin lambda variable 5-52ENSG0000021164343
IGLV11-55 / immunoglobulin lambda variable 11-55 (non-functional)ENSG0000021164141
IGLV5-48 / immunoglobulin lambda variable 5-48 (non-functional)ENSG0000021164740
IGLV9-49 / A0A0B4J1Y8 / immunoglobulin lambda variable 9-49ENSG0000022335036
IGLV4-60 / A0A075B6I1 / immunoglobulin lambda variable 4-60ENSG0000021163935
Q9UKI3 / VPREB3 / V-set pre-B cell surrogate light chain 3ENSG0000012821834
IGLV4-3 / A0A075B6K6 / immunoglobulin lambda variable 4-3ENSG0000021167233
IGLV4-69 / A0A075B6H9 / immunoglobulin lambda variable 4-69ENSG0000021163733


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013106  Immunoglobulin V-set domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002377 immunoglobulin production IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000128322 IGLL1 / P15814 / immunoglobulin lambda like polypeptide 1  / complex / reaction
 ENSG00000211899 IGHM / P01871 / immunoglobulin heavy constant mu  / complex / reaction
 ENSG00000128218 Q9UKI3 / VPREB3 / V-set pre-B cell surrogate light chain 3  / reaction / complex
 ENSG00000169575 P12018 / VPREB1 / V-set pre-B cell surrogate light chain 1  / reaction / complex






 

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