ENSG00000128886


Homo sapiens

Features
Gene ID: ENSG00000128886
  
Biological name :ELL3
  
Synonyms : ELL3 / elongation factor for RNA polymerase II 3 / Q9HB65
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q15.3
Gene start: 43772600
Gene end: 43777543
  
Corresponding Affymetrix probe sets: 219517_at (Human Genome U133 Plus 2.0 Array)   219518_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000320346
Ensembl peptide - ENSP00000404209
NCBI entrez gene - 80237     See in Manteia.
OMIM - 609885
RefSeq - NM_025165
RefSeq Peptide - NP_079441
swissprot - C9JHD8
swissprot - Q9HB65
Ensembl - ENSG00000128886
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-13k12.2ENSDARG00000038121Danio rerio
 Ell3ENSMUSG00000027246Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELL2 / O00472 / elongation factor for RNA polymerase II 2ENSG0000011898530
ELL / P55199 / elongation factor for RNA polymerase IIENSG0000010565629
Q8N4S9 / MARVELD2 / MARVEL domain containing 2ENSG0000015293915
OCEL1 / Q9H607 / occludin/ELL domain containing 1ENSG0000009933010


Protein motifs (from Interpro)
Interpro ID Name
 IPR010844  Occludin homology domain
 IPR019464  RNA polymerase II elongation factor ELL, N-terminal
 IPR031175  RNA polymerase II elongation factor ELL3
 IPR031176  ELL/occludin family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006354 DNA-templated transcription, elongation IDA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0007283 spermatogenesis NAS
 biological_processGO:0010717 regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation IDA
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:1901797 negative regulation of signal transduction by p53 class mediator IEA
 biological_processGO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IEA
 biological_processGO:2000179 positive regulation of neural precursor cell proliferation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0008023 transcription elongation factor complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035326 enhancer binding IEA


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000128915 ICE2 / Q659A1 / interactor of little elongation complex ELL subunit 2  / complex
 ENSG00000144161 ZC3H8 / Q8N5P1 / zinc finger CCCH-type containing 8  / complex
 ENSG00000164151 ICE1 / Q9Y2F5 / interactor of little elongation complex ELL subunit 1  / complex






 

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