ENSG00000118985


Homo sapiens

Features
Gene ID: ENSG00000118985
  
Biological name :ELL2
  
Synonyms : ELL2 / elongation factor for RNA polymerase II 2 / O00472
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q15
Gene start: 95885098
Gene end: 95962071
  
Corresponding Affymetrix probe sets: 214445_at (Human Genome U133 Plus 2.0 Array)   214446_at (Human Genome U133 Plus 2.0 Array)   226099_at (Human Genome U133 Plus 2.0 Array)   226982_at (Human Genome U133 Plus 2.0 Array)   240038_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000423915
Ensembl peptide - ENSP00000489270
Ensembl peptide - ENSP00000237853
Ensembl peptide - ENSP00000420894
NCBI entrez gene - 22936     See in Manteia.
OMIM - 601874
RefSeq - XM_017009243
RefSeq - XM_006714575
RefSeq - XM_017009239
RefSeq - XM_017009240
RefSeq - XM_017009241
RefSeq - XM_017009242
RefSeq - NM_012081
RefSeq Peptide - NP_036213
swissprot - D6RC27
swissprot - H0Y8G1
swissprot - A0A0U1RR08
swissprot - O00472
Ensembl - ENSG00000118985
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ell2ENSDARG00000006251Danio rerio
 ELL2ENSGALG00000014678Gallus gallus
 Ell2ENSMUSG00000001542Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELL / P55199 / elongation factor for RNA polymerase IIENSG0000010565648
ELL3 / Q9HB65 / elongation factor for RNA polymerase II 3ENSG0000012888619
Q8N4S9 / MARVELD2 / MARVEL domain containing 2ENSG0000015293913
OCEL1 / Q9H607 / occludin/ELL domain containing 1ENSG000000993309


Protein motifs (from Interpro)
Interpro ID Name
 IPR010844  Occludin homology domain
 IPR019464  RNA polymerase II elongation factor ELL, N-terminal
 IPR031176  ELL/occludin family
 IPR031179  RNA polymerase II elongation factor ELL2
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0042795 snRNA transcription by RNA polymerase II TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0008023 transcription elongation factor complex IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RNA polymerase II transcribes snRNA genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000144161 ZC3H8 / Q8N5P1 / zinc finger CCCH-type containing 8  / complex
 ENSG00000164151 ICE1 / Q9Y2F5 / interactor of little elongation complex ELL subunit 1  / complex
 ENSG00000128915 ICE2 / Q659A1 / interactor of little elongation complex ELL subunit 2  / complex






 

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