ENSG00000105656


Homo sapiens

Features
Gene ID: ENSG00000105656
  
Biological name :ELL
  
Synonyms : ELL / elongation factor for RNA polymerase II / P55199
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 18442663
Gene end: 18522127
  
Corresponding Affymetrix probe sets: 1565254_s_at (Human Genome U133 Plus 2.0 Array)   204095_s_at (Human Genome U133 Plus 2.0 Array)   204096_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000262809
Ensembl peptide - ENSP00000475648
Ensembl peptide - ENSP00000475681
NCBI entrez gene - 8178     See in Manteia.
OMIM - 600284
RefSeq - XM_017027337
RefSeq - NM_006532
RefSeq - XM_017027335
RefSeq - XM_017027336
RefSeq Peptide - NP_006523
swissprot - U3KQA3
swissprot - P55199
swissprot - U3KQ90
Ensembl - ENSG00000105656
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ellENSDARG00000000568Danio rerio
 ELLENSGALG00000033513Gallus gallus
 EllENSMUSG00000070002Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ELL2 / O00472 / elongation factor for RNA polymerase II 2ENSG0000011898549
ELL3 / Q9HB65 / elongation factor for RNA polymerase II 3ENSG0000012888619
Q8N4S9 / MARVELD2 / MARVEL domain containing 2ENSG0000015293914
OCEL1 / Q9H607 / occludin/ELL domain containing 1ENSG000000993309


Protein motifs (from Interpro)
Interpro ID Name
 IPR010844  Occludin homology domain
 IPR019464  RNA polymerase II elongation factor ELL, N-terminal
 IPR031176  ELL/occludin family
 IPR031184  RNA polymerase II elongation factor ELL
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IEA
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0032786 positive regulation of DNA-templated transcription, elongation TAS
 biological_processGO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter IMP
 biological_processGO:0042795 snRNA transcription by RNA polymerase II IEA
 biological_processGO:0042796 snRNA transcription by RNA polymerase III IMP
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0008023 transcription elongation factor complex IEA
 cellular_componentGO:0015030 Cajal body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0035327 transcriptionally active chromatin IDA
 cellular_componentGO:0035363 histone locus body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019902 phosphatase binding IDA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
RNA Polymerase II Transcription Elongation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000164151 ICE1 / Q9Y2F5 / interactor of little elongation complex ELL subunit 1  / complex
 ENSG00000144161 ZC3H8 / Q8N5P1 / zinc finger CCCH-type containing 8  / complex
 ENSG00000128915 ICE2 / Q659A1 / interactor of little elongation complex ELL subunit 2  / complex






 

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