ENSG00000129158


Homo sapiens

Features
Gene ID: ENSG00000129158
  
Biological name :SERGEF
  
Synonyms : Q9UGK8 / secretion regulating guanine nucleotide exchange factor / SERGEF
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: p15.1
Gene start: 17788048
Gene end: 18013162
  
Corresponding Affymetrix probe sets: 220482_s_at (Human Genome U133 Plus 2.0 Array)   223483_at (Human Genome U133 Plus 2.0 Array)   232983_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433884
Ensembl peptide - ENSP00000437297
Ensembl peptide - ENSP00000436648
Ensembl peptide - ENSP00000436111
Ensembl peptide - ENSP00000436080
Ensembl peptide - ENSP00000435898
Ensembl peptide - ENSP00000435003
Ensembl peptide - ENSP00000434330
Ensembl peptide - ENSP00000434188
Ensembl peptide - ENSP00000265965
Ensembl peptide - ENSP00000431314
Ensembl peptide - ENSP00000431490
Ensembl peptide - ENSP00000432763
Ensembl peptide - ENSP00000433383
Ensembl peptide - ENSP00000433870
NCBI entrez gene - 26297     See in Manteia.
OMIM - 606051
RefSeq - NM_012139
RefSeq Peptide - NP_036271
swissprot - E9PL52
swissprot - E9PIV0
swissprot - E9PIU4
swissprot - B4DFC0
swissprot - G3V1B4
swissprot - H0YD20
swissprot - H0YDC8
swissprot - H0YE53
swissprot - H0YEL8
swissprot - H0YEV5
swissprot - E9PS70
swissprot - Q9UGK8
swissprot - E9PR50
swissprot - E9PMV6
Ensembl - ENSG00000129158
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sergefENSDARG00000070986Danio rerio
 SERGEFENSGALG00000006231Gallus gallus
 Q80YD6ENSMUSG00000030839Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPGR / Q92834 / retinitis pigmentosa GTPase regulatorENSG0000015631325
RCC1L / Q96I51 / RCC1 likeENSG0000027452319
RCC1 / P18754 / regulator of chromosome condensation 1ENSG0000018019819
RCC2 / Q9P258 / regulator of chromosome condensation 2ENSG0000017905119
O95199 / RCBTB2 / RCC1 and BTB domain containing protein 2ENSG0000013616119
Q8NDN9 / RCBTB1 / RCC1 and BTB domain containing protein 1ENSG0000013614418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0050709 negative regulation of protein secretion IDA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016235 aggresome IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005087 Ran guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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