ENSG00000180198


Homo sapiens

Features
Gene ID: ENSG00000180198
  
Biological name :RCC1
  
Synonyms : P18754 / RCC1 / regulator of chromosome condensation 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.3
Gene start: 28505943
Gene end: 28539300
  
Corresponding Affymetrix probe sets: 206499_s_at (Human Genome U133 Plus 2.0 Array)   215747_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362939
Ensembl peptide - ENSP00000472057
Ensembl peptide - ENSP00000413644
Ensembl peptide - ENSP00000405258
Ensembl peptide - ENSP00000402740
Ensembl peptide - ENSP00000402260
Ensembl peptide - ENSP00000394650
Ensembl peptide - ENSP00000381931
Ensembl peptide - ENSP00000362937
Ensembl peptide - ENSP00000362938
NCBI entrez gene - 1104     See in Manteia.
OMIM - 179710
RefSeq - NM_001048199
RefSeq - NM_001269
RefSeq - NM_001048195
RefSeq - NM_001048194
RefSeq Peptide - NP_001041664
RefSeq Peptide - NP_001260
RefSeq Peptide - NP_001041659
RefSeq Peptide - NP_001041660
swissprot - Q5T081
swissprot - C9JRH2
swissprot - C9JQZ4
swissprot - C9JMJ4
swissprot - C9J3R0
swissprot - A0A0S2Z404
swissprot - M0R1Q8
swissprot - P18754
swissprot - C9JW69
Ensembl - ENSG00000180198
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rcc1ENSDARG00000037158Danio rerio
 RCC1ENSGALG00000030097Gallus gallus
 Rcc1ENSMUSG00000028896Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RPGR / Q92834 / retinitis pigmentosa GTPase regulatorENSG0000015631326
RCC1L / Q96I51 / RCC1 likeENSG0000027452321
RCC2 / Q9P258 / regulator of chromosome condensation 2ENSG0000017905120
Q9UGK8 / SERGEF / secretion regulating guanine nucleotide exchange factorENSG0000012915819
O95199 / RCBTB2 / RCC1 and BTB domain containing protein 2ENSG0000013616119
Q8NDN9 / RCBTB1 / RCC1 and BTB domain containing protein 1ENSG0000013614418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000408  Regulator of chromosome condensation, RCC1
 IPR009091  Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007052 mitotic spindle organization IDA
 biological_processGO:0007059 chromosome segregation IMP
 biological_processGO:0007088 regulation of mitotic nuclear division IDA
 biological_processGO:0016032 viral process TAS
 biological_processGO:0051225 spindle assembly IMP
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0000785 chromatin IDA
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005087 Ran guanyl-nucleotide exchange factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008536 Ran GTPase binding IDA
 molecular_functionGO:0031491 nucleosome binding IMP
 molecular_functionGO:0031492 nucleosomal DNA binding IDA
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0043199 sulfate binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
Rev-mediated nuclear export of HIV RNA
Nuclear import of Rev protein


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132341 RAN / P62826 / RAN, member RAS oncogene family  / reaction






 

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