ENSG00000130035


Homo sapiens

Features
Gene ID: ENSG00000130035
  
Biological name :GALNT8
  
Synonyms : GALNT8 / P17658 / polypeptide N-acetylgalactosaminyltransferase 8 / Q9NY28
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.32
Gene start: 4720341
Gene end: 4851927
  
Corresponding Affymetrix probe sets: 1553347_s_at (Human Genome U133 Plus 2.0 Array)   205616_at (Human Genome U133 Plus 2.0 Array)   220929_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000444876
Ensembl peptide - ENSP00000252318
Ensembl peptide - ENSP00000408321
Ensembl peptide - ENSP00000440383
NCBI entrez gene - 26290     See in Manteia.
NCBI entrez gene - 3742     See in Manteia.
OMIM - 176257
OMIM - 606250
RefSeq - XM_017019272
RefSeq - NM_002235
RefSeq - NM_017417
RefSeq - XM_005253686
RefSeq - XM_011520955
RefSeq - XM_017019270
RefSeq - XM_017019271
RefSeq Peptide - NP_002226
RefSeq Peptide - NP_059113
swissprot - H0YGU9
swissprot - Q9NY28
swissprot - H0YFU9
swissprot - P17658
Ensembl - ENSG00000130035
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 galnt8a.1ENSDARG00000012355Danio rerio
 galnt8a.1ENSDARG00000115940Danio rerio
 galnt8a.2ENSDARG00000011869Danio rerio
 galnt8b.1ENSDARG00000045851Danio rerio
 galnt8b.2ENSDARG00000095324Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P9A2 / GALNT18 / polypeptide N-acetylgalactosaminyltransferase 18ENSG0000011032844
GALNT9 / Q9HCQ5 / polypeptide N-acetylgalactosaminyltransferase 9ENSG0000018287042
Q6IS24 / GALNT17 / polypeptide N-acetylgalactosaminyltransferase 17ENSG0000018527439
Q8N3T1 / GALNT15 / polypeptide N-acetylgalactosaminyltransferase 15ENSG0000013138627
Q86SR1 / GALNT10 / polypeptide N-acetylgalactosaminyltransferase 10ENSG0000016457426
GALNT7 / Q86SF2 / polypeptide N-acetylgalactosaminyltransferase 7ENSG0000010958625
Q49A17 / GALNTL6 / polypeptide N-acetylgalactosaminyltransferase like 6ENSG0000017447325


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR000772  Ricin B, lectin domain
 IPR001173  Glycosyltransferase 2-like
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003972  Potassium channel, voltage dependent, Kv1
 IPR004053  Potassium channel, voltage dependent, Kv1.6
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR028325  Voltage-gated potassium channel
 IPR029044  Nucleotide-diphospho-sugar transferases
 IPR035992  Ricin B-like lectins


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport TAS
 biological_processGO:0016266 O-glycan processing TAS
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0008076 voltage-gated potassium channel complex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0034705 potassium channel complex ISS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004653 polypeptide N-acetylgalactosaminyltransferase activity TAS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity TAS
 molecular_functionGO:0005251 delayed rectifier potassium channel activity IDA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
O-linked glycosylation of mucins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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