ENSG00000130520


Homo sapiens

Features
Gene ID: ENSG00000130520
  
Biological name :LSM4
  
Synonyms : LSM4 / LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated / Q9Y4Z0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 18306230
Gene end: 18323274
  
Corresponding Affymetrix probe sets: 202736_s_at (Human Genome U133 Plus 2.0 Array)   202737_s_at (Human Genome U133 Plus 2.0 Array)   212924_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000469028
Ensembl peptide - ENSP00000469468
Ensembl peptide - ENSP00000475950
Ensembl peptide - ENSP00000477443
NCBI entrez gene - 25804     See in Manteia.
OMIM - 607284
RefSeq - NM_001252129
RefSeq - NM_012321
RefSeq Peptide - NP_001239058
RefSeq Peptide - NP_036453
swissprot - V9GZ56
swissprot - Q9Y4Z0
swissprot - U3KQK1
swissprot - M0QXB0
Ensembl - ENSG00000130520
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lsm4ENSDARG00000023852Danio rerio
 LSM4ENSGALG00000003385Gallus gallus
 Lsm4ENSMUSG00000031848Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001163  LSM domain, eukaryotic/archaea-type
 IPR010920  LSM domain superfamily
 IPR027141  Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3
 IPR034101  Sm-like protein Lsm4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000245 spliceosomal complex assembly IBA
 biological_processGO:0000387 spliceosomal snRNP assembly IBA
 biological_processGO:0000398 mRNA splicing, via spliceosome IEA
 biological_processGO:0000956 nuclear-transcribed mRNA catabolic process IEA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0008380 RNA splicing TAS
 biological_processGO:0033962 cytoplasmic mRNA processing body assembly IBA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay TAS
 cellular_componentGO:0000932 P-body IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005681 spliceosomal complex IEA
 cellular_componentGO:0005688 U6 snRNP TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0097526 spliceosomal tri-snRNP complex IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017070 U6 snRNA binding IBA
 molecular_functionGO:0042731 PH domain binding IDA


Pathways (from Reactome)
Pathway description
mRNA decay by 5 to 3 exoribonuclease
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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