ENSG00000130545


Homo sapiens

Features
Gene ID: ENSG00000130545
  
Biological name :CRB3
  
Synonyms : CRB3 / crumbs 3, cell polarity complex component / Q9BUF7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 6463777
Gene end: 6467221
  
Corresponding Affymetrix probe sets: 232609_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310123
Ensembl peptide - ENSP00000349204
Ensembl peptide - ENSP00000469707
Ensembl peptide - ENSP00000472010
NCBI entrez gene - 92359     See in Manteia.
OMIM - 609737
RefSeq - XM_017027471
RefSeq - NM_139161
RefSeq - NM_174881
RefSeq - NM_174882
RefSeq Peptide - NP_777377
RefSeq Peptide - NP_777378
RefSeq Peptide - NP_631900
swissprot - Q9BUF7
Ensembl - ENSG00000130545
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Crb3ENSMUSG00000044279Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0070830 bicellular tight junction assembly TAS
 biological_processGO:0072659 protein localization to plasma membrane IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IPI
 molecular_functionGO:0019904 protein domain specific binding IPI


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132849 PATJ / Q8NI35 / PATJ, crumbs cell polarity complex component  / complex / reaction
 ENSG00000072415 MPP5 / Q8N3R9 / membrane palmitoylated protein 5  / reaction / complex






 

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contact: otassy@igbmc.fr