ENSG00000132849


Homo sapiens

Features
Gene ID: ENSG00000132849
  
Biological name :PATJ
  
Synonyms : PATJ / PATJ, crumbs cell polarity complex component / Q8NI35
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.3
Gene start: 61742406
Gene end: 62178675
  
Corresponding Affymetrix probe sets: 214493_s_at (Human Genome U133 Plus 2.0 Array)   214705_at (Human Genome U133 Plus 2.0 Array)   223681_s_at (Human Genome U133 Plus 2.0 Array)   232041_at (Human Genome U133 Plus 2.0 Array)   239173_at (Human Genome U133 Plus 2.0 Array)   240570_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000360200
Ensembl peptide - ENSP00000494824
Ensembl peptide - ENSP00000494277
Ensembl peptide - ENSP00000489475
Ensembl peptide - ENSP00000489335
Ensembl peptide - ENSP00000489200
Ensembl peptide - ENSP00000489159
Ensembl peptide - ENSP00000489130
Ensembl peptide - ENSP00000479041
Ensembl peptide - ENSP00000433669
Ensembl peptide - ENSP00000307496
Ensembl peptide - ENSP00000326199
NCBI entrez gene - 10207     See in Manteia.
OMIM - 603199
RefSeq - XM_017000001
RefSeq - XM_011540463
RefSeq - XM_011540464
RefSeq - XM_011540465
RefSeq - XM_011540466
RefSeq - XM_011540467
RefSeq - XM_011540468
RefSeq - XM_011540469
RefSeq - XM_011540470
RefSeq - XM_016999998
RefSeq - XM_016999999
RefSeq - XM_017000000
RefSeq - NM_001350145
RefSeq - NM_176877
RefSeq - XM_005270341
RefSeq - XM_005270347
RefSeq - XM_006710278
RefSeq - XM_011540462
RefSeq Peptide - NP_001337074
RefSeq Peptide - NP_795352
swissprot - A0A0U1RQW4
swissprot - A0A0U1RQT2
swissprot - A0A0U1RQR3
swissprot - A0A0U1RRD7
swissprot - A0A0X1KG69
swissprot - Q8NI35
swissprot - B4DE90
swissprot - A0A087WUZ6
swissprot - A0A0U1RR46
Ensembl - ENSG00000132849
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 patjENSDARG00000024964Danio rerio
 ENSGALG00000010934Gallus gallus
 ENSGALG00000038993Gallus gallus
 PatjENSMUSG00000061859Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MPDZ / O75970 / multiple PDZ domain crumbs cell polarity complex componentENSG0000010718644
PDZD2 / O15018 / PDZ domain containing 2ENSG0000013340117
IL16 / Q14005 / interleukin 16ENSG0000017234911
PARD3 / Q8TEW0 / par-3 family cell polarity regulatorENSG0000014849811
PARD3B / Q8TEW8 / par-3 family cell polarity regulator betaENSG0000011611710
LNX2 / Q8N448 / ligand of numb-protein X 2ENSG000001395177
LNX1 / Q8TBB1 / ligand of numb-protein X 1ENSG000000722017


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR004172  L27 domain
 IPR015132  L27-2
 IPR036034  PDZ superfamily
 IPR036892  L27 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035556 intracellular signal transduction NAS
 biological_processGO:0070830 bicellular tight junction assembly TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005923 bicellular tight junction IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0030054 cell junction IDA
 cellular_componentGO:0045177 apical part of cell IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000130545 CRB3 / Q9BUF7 / crumbs 3, cell polarity complex component  / complex / reaction
 ENSG00000072415 MPP5 / Q8N3R9 / membrane palmitoylated protein 5  / reaction / complex






 

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