ENSG00000072201


Homo sapiens

Features
Gene ID: ENSG00000072201
  
Biological name :LNX1
  
Synonyms : ligand of numb-protein X 1 / LNX1 / Q8TBB1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q12
Gene start: 53459301
Gene end: 53701405
  
Corresponding Affymetrix probe sets: 223611_s_at (Human Genome U133 Plus 2.0 Array)   223612_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302879
Ensembl peptide - ENSP00000421897
Ensembl peptide - ENSP00000426445
Ensembl peptide - ENSP00000425135
Ensembl peptide - ENSP00000424364
Ensembl peptide - ENSP00000423344
Ensembl peptide - ENSP00000263925
NCBI entrez gene - 84708     See in Manteia.
OMIM - 609732
RefSeq - XM_017008776
RefSeq - NM_001126328
RefSeq - NM_032622
RefSeq - XM_005265785
RefSeq Peptide - NP_116011
RefSeq Peptide - NP_001119800
swissprot - A0A0B4J209
swissprot - Q8TBB1
swissprot - D6RB76
swissprot - D6RAH9
swissprot - D6RE08
Ensembl - ENSG00000072201
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lnx1ENSDARG00000043323Danio rerio
 LNX1ENSGALG00000013940Gallus gallus
 Lnx1ENSMUSG00000029228Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LNX2 / Q8N448 / ligand of numb-protein X 2ENSG0000013951748
PDZD2 / O15018 / PDZ domain containing 2ENSG0000013340120
MPDZ / O75970 / multiple PDZ domain crumbs cell polarity complex componentENSG0000010718619
PATJ / Q8NI35 / PATJ, crumbs cell polarity complex componentENSG0000013284918
PARD3 / Q8TEW0 / par-3 family cell polarity regulatorENSG0000014849816
IL16 / Q14005 / interleukin 16ENSG0000017234916
PARD3B / Q8TEW8 / par-3 family cell polarity regulator betaENSG0000011611714


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR018957  Zinc finger, C3HC4 RING-type
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051260 protein homooligomerization IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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