ENSMUSG00000029228


Mus musculus

Features
Gene ID: ENSMUSG00000029228
  
Biological name :Lnx1
  
Synonyms : ligand of numb-protein X 1 / Lnx1 / O70263
  
Possible biological names infered from orthology : Q8TBB1
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: C3.3
Gene start: 74592447
Gene end: 74702912
  
Corresponding Affymetrix probe sets: 10530666 (MoGene1.0st)   1450251_a_at (Mouse Genome 430 2.0 Array)   1455825_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000113565
Ensembl peptide - ENSMUSP00000113837
Ensembl peptide - ENSMUSP00000121094
Ensembl peptide - ENSMUSP00000120886
Ensembl peptide - ENSMUSP00000117935
Ensembl peptide - ENSMUSP00000040098
Ensembl peptide - ENSMUSP00000084405
Ensembl peptide - ENSMUSP00000109159
Ensembl peptide - ENSMUSP00000113035
NCBI entrez gene - 16924     See in Manteia.
MGI - MGI:1278335
RefSeq - NM_001159580
RefSeq - XM_017320691
RefSeq - XM_017320690
RefSeq - XM_006504254
RefSeq - NM_010727
RefSeq - NM_001159577
RefSeq - NM_001159578
RefSeq - NM_001159579
RefSeq Peptide - NP_001153049
RefSeq Peptide - NP_001153050
RefSeq Peptide - NP_001153051
RefSeq Peptide - NP_001153052
RefSeq Peptide - NP_001346003
RefSeq Peptide - NP_034857
swissprot - D6RHN7
swissprot - A4QPD4
swissprot - E9Q6Q0
swissprot - E9Q4N3
swissprot - O70263
swissprot - F7AT68
Ensembl - ENSMUSG00000029228
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lnx1ENSDARG00000043323Danio rerio
 LNX1ENSGALG00000013940Gallus gallus
 LNX1ENSG00000072201Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Lnx2 / Q91XL2 / Ligand of Numb protein X 2 / Q8N448*ENSMUSG0000001652048
Pdzd2 / PDZ domain containing 2 / O15018*ENSMUSG0000002219720
Patj / Q63ZW7 / Mus musculus PATJ, crumbs cell polarity complex component (Patj), transcript variant 5, mRNA. / Q8NI35* / PATJ, crumbs cell polarity complex component*ENSMUSG0000006185919
Mpdz / Q8VBX6 / multiple PDZ domain protein / O75970* / multiple PDZ domain crumbs cell polarity complex component*ENSMUSG0000002840218
Pard3 / Q99NH2 / par-3 family cell polarity regulator / Q8TEW0*ENSMUSG0000002581216
Il16 / O54824 / Pro-interleukin-16 Interleukin-16 / Q14005* / interleukin 16*ENSMUSG0000000174115
Pard3b / Q9CSB4 / par-3 family cell polarity regulator beta / Q8TEW8*ENSMUSG0000005206214


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051260 protein homooligomerization IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030165 PDZ domain binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008169 increased B-1b cell number "greater number of the B-1 B cell subset not bearing the CD5 surface marker, but having other phenotypic attributes of a B-1 B cell" [CL:0000821, PMID:11861604]
Show

Allelic Composition: Mecp2tm1.1Irsf/Y
Genetic Background: involves: 129S/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr