ENSMUSG00000001741


Mus musculus

Features
Gene ID: ENSMUSG00000001741
  
Biological name :Il16
  
Synonyms : Il16 / O54824 / Pro-interleukin-16 Interleukin-16
  
Possible biological names infered from orthology : interleukin 16 / Q14005
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: D3
Gene start: 83642825
Gene end: 83745726
  
Corresponding Affymetrix probe sets: 10565218 (MoGene1.0st)   1417391_a_at (Mouse Genome 430 2.0 Array)   1443796_at (Mouse Genome 430 2.0 Array)   1447814_x_at (Mouse Genome 430 2.0 Array)   1448686_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001792
Ensembl peptide - ENSMUSP00000122022
Ensembl peptide - ENSMUSP00000122813
Ensembl peptide - ENSMUSP00000146496
Ensembl peptide - ENSMUSP00000118516
NCBI entrez gene - 16170     See in Manteia.
MGI - MGI:1270855
RefSeq - XM_017321990
RefSeq - XM_006507386
RefSeq - XM_011241680
RefSeq - XM_011241681
RefSeq - XM_017321989
RefSeq - NM_010551
RefSeq - XM_006507385
RefSeq Peptide - NP_034681
swissprot - D6RI15
swissprot - D3Z3C7
swissprot - O54824
Ensembl - ENSMUSG00000001741
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il16ENSDARG00000102908Danio rerio
 IL16ENSGALG00000006388Gallus gallus
 IL16ENSG00000172349Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pdzd2 / PDZ domain containing 2 / O15018*ENSMUSG0000002219728
Mpdz / Q8VBX6 / multiple PDZ domain protein / O75970* / multiple PDZ domain crumbs cell polarity complex component*ENSMUSG0000002840215
Patj / Q63ZW7 / Mus musculus PATJ, crumbs cell polarity complex component (Patj), transcript variant 5, mRNA. / Q8NI35* / PATJ, crumbs cell polarity complex component*ENSMUSG0000006185915
Pard3 / Q99NH2 / par-3 family cell polarity regulator / Q8TEW0*ENSMUSG0000002581212
Pard3b / Q9CSB4 / par-3 family cell polarity regulator beta / Q8TEW8*ENSMUSG0000005206212
Lnx1 / O70263 / ligand of numb-protein X 1 / Q8TBB1*ENSMUSG000000292288
Lnx2 / Q91XL2 / Ligand of Numb protein X 2 / Q8N448*ENSMUSG000000165208


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR020450  Interleukin-16
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030595 leukocyte chemotaxis IDA
 biological_processGO:0050930 induction of positive chemotaxis IDA
 biological_processGO:0051924 regulation of calcium ion transport ISO
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0005125 cytokine activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042609 CD4 receptor binding ISO


Pathways (from Reactome)
Pathway description
Other interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002444 abnormal T cell physiology "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Bmpr1atm2.1Bhr/Bmpr1atm2.2Bhr,Tg(Gdf5-cre-ALPP)1Kng/0
Genetic Background: involves: 129 * C57BL/6 * FVB/N-Tg(Gdf5-cre-ALPP)1Kng

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023274 Cd4 / P06332 / T-cell surface glycoprotein CD4 / P01730* / CD4 molecule*  / complex / reaction
 ENSMUSG00000031628 Casp3 / P70677 / Caspase-3 Caspase-3 subunit p17 Caspase-3 subunit p12 / P42574* / caspase 3*  / reaction






 

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