ENSG00000172349


Homo sapiens

Features
Gene ID: ENSG00000172349
  
Biological name :IL16
  
Synonyms : IL16 / interleukin 16 / Q14005
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q25.1
Gene start: 81159575
Gene end: 81314058
  
Corresponding Affymetrix probe sets: 1555016_at (Human Genome U133 Plus 2.0 Array)   209827_s_at (Human Genome U133 Plus 2.0 Array)   209828_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000456972
Ensembl peptide - ENSP00000453250
Ensembl peptide - ENSP00000454636
Ensembl peptide - ENSP00000302935
Ensembl peptide - ENSP00000378147
Ensembl peptide - ENSP00000378155
Ensembl peptide - ENSP00000452738
Ensembl peptide - ENSP00000453131
Ensembl peptide - ENSP00000453214
NCBI entrez gene - 3603     See in Manteia.
OMIM - 603035
RefSeq - XM_017022146
RefSeq - XM_005254342
RefSeq - XM_005254346
RefSeq - XM_011521519
RefSeq - XM_011521520
RefSeq - XM_017022140
RefSeq - XM_017022141
RefSeq - XM_017022142
RefSeq - XM_017022143
RefSeq - XM_017022144
RefSeq - XM_017022145
RefSeq - NM_001172128
RefSeq - NM_004513
RefSeq - NM_172217
RefSeq Peptide - NP_004504
RefSeq Peptide - NP_757366
RefSeq Peptide - NP_001165599
swissprot - H3BN12
swissprot - H3BT15
swissprot - H0YLB1
swissprot - Q14005
swissprot - H0YKB7
swissprot - H0YLH9
swissprot - H0YLL1
Ensembl - ENSG00000172349
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il16ENSDARG00000102908Danio rerio
 IL16ENSGALG00000006388Gallus gallus
 Il16ENSMUSG00000001741Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PDZD2 / O15018 / PDZ domain containing 2ENSG0000013340131
MPDZ / O75970 / multiple PDZ domain crumbs cell polarity complex componentENSG0000010718616
PATJ / Q8NI35 / PATJ, crumbs cell polarity complex componentENSG0000013284914
PARD3B / Q8TEW8 / par-3 family cell polarity regulator betaENSG0000011611712
PARD3 / Q8TEW0 / par-3 family cell polarity regulatorENSG0000014849812
LNX1 / Q8TBB1 / ligand of numb-protein X 1ENSG000000722019
LNX2 / Q8N448 / ligand of numb-protein X 2ENSG000001395178


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR020450  Interleukin-16
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0030595 leukocyte chemotaxis IEA
 biological_processGO:0050930 induction of positive chemotaxis IEA
 biological_processGO:0051924 regulation of calcium ion transport IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042609 CD4 receptor binding IPI


Pathways (from Reactome)
Pathway description
Other interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000010610 CD4 / P01730 / CD4 molecule  / complex / reaction
 ENSG00000164305 CASP3 / P42574 / caspase 3  / reaction






 

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