ENSG00000139517


Homo sapiens

Features
Gene ID: ENSG00000139517
  
Biological name :LNX2
  
Synonyms : ligand of numb-protein X 2 / LNX2 / Q8N448
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q12.2
Gene start: 27545911
Gene end: 27620404
  
Corresponding Affymetrix probe sets: 227569_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000325929
NCBI entrez gene - 222484     See in Manteia.
OMIM - 609733
RefSeq - XM_017020434
RefSeq - NM_153371
RefSeq - XM_011534995
RefSeq Peptide - NP_699202
swissprot - Q8N448
Ensembl - ENSG00000139517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lnx2aENSDARG00000029177Danio rerio
 ENSGALG00000017096Gallus gallus
 ENSGALG00000038864Gallus gallus
 Lnx2ENSMUSG00000016520Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LNX1 / Q8TBB1 / ligand of numb-protein X 1ENSG0000007220150
PDZD2 / O15018 / PDZ domain containing 2ENSG0000013340120
MPDZ / O75970 / multiple PDZ domain crumbs cell polarity complex componentENSG0000010718619
PATJ / Q8NI35 / PATJ, crumbs cell polarity complex componentENSG0000013284919
IL16 / Q14005 / interleukin 16ENSG0000017234916
PARD3 / Q8TEW0 / par-3 family cell polarity regulatorENSG0000014849815
PARD3B / Q8TEW8 / par-3 family cell polarity regulator betaENSG0000011611714


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0051260 protein homooligomerization IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030165 PDZ domain binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr