ENSG00000131355


Homo sapiens

Features
Gene ID: ENSG00000131355
  
Biological name :ADGRE3
  
Synonyms : ADGRE3 / adhesion G protein-coupled receptor E3 / Q9BY15
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 14619117
Gene end: 14690027
  
Corresponding Affymetrix probe sets: 210724_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000253673
Ensembl peptide - ENSP00000396208
Ensembl peptide - ENSP00000469965
Ensembl peptide - ENSP00000471853
Ensembl peptide - ENSP00000340758
NCBI entrez gene - 84658     See in Manteia.
OMIM - 606101
RefSeq - XM_017027383
RefSeq - NM_001289158
RefSeq - NM_001289159
RefSeq - NM_032571
RefSeq - XM_011528374
RefSeq Peptide - NP_001276088
RefSeq Peptide - NP_115960
RefSeq Peptide - NP_001276087
swissprot - Q9BY15
swissprot - M0QYN7
swissprot - E7EW83
swissprot - M0R1G2
Ensembl - ENSG00000131355
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgre10ENSDARG00000075855Danio rerio
 adgre14ENSDARG00000056062Danio rerio
 adgre15ENSDARG00000096588Danio rerio
 adgre16ENSDARG00000096622Danio rerio
 adgre17ENSDARG00000095297Danio rerio
 adgre18ENSDARG00000096644Danio rerio
 adgre19ENSDARG00000096649Danio rerio
 adgre6ENSDARG00000095494Danio rerio
 adgre7ENSDARG00000041399Danio rerio
 adgre8ENSDARG00000079050Danio rerio
 adgre9ENSDARG00000096577Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRE2 / Q9UHX3 / adhesion G protein-coupled receptor E2ENSG0000012750755
ADGRE1 / Q14246 / adhesion G protein-coupled receptor E1ENSG0000017483738
ADGRE5 / P48960 / adhesion G protein-coupled receptor E5ENSG0000012314635
ADGRL1 / O94910 / adhesion G protein-coupled receptor L1ENSG0000007207131
ADGRL2 / O95490 / adhesion G protein-coupled receptor L2ENSG0000011711431
ADGRL3 / Q9HAR2 / adhesion G protein-coupled receptor L3ENSG0000015047131
ADGRL4 / Q9HBW9 / adhesion G protein-coupled receptor L4ENSG0000016261825
ADGRD1 / Q6QNK2 / adhesion G protein-coupled receptor D1ENSG0000011145223


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000203  GPS motif
 IPR000742  EGF-like domain
 IPR000832  GPCR, family 2, secretin-like
 IPR001740  GPCR family 2, EMR1-like receptor
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR018996  Man1-Src1p-C-terminal domain
 IPR032471  GAIN domain, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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