ENSG00000072071


Homo sapiens

Features
Gene ID: ENSG00000072071
  
Biological name :ADGRL1
  
Synonyms : ADGRL1 / adhesion G protein-coupled receptor L1 / O94910
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.12
Gene start: 14147743
Gene end: 14206187
  
Corresponding Affymetrix probe sets: 203488_at (Human Genome U133 Plus 2.0 Array)   219145_at (Human Genome U133 Plus 2.0 Array)   47560_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000355328
Ensembl peptide - ENSP00000468197
Ensembl peptide - ENSP00000468711
Ensembl peptide - ENSP00000340688
Ensembl peptide - ENSP00000465453
NCBI entrez gene - 22859     See in Manteia.
OMIM - 616416
RefSeq - XM_017026480
RefSeq - XM_011527801
RefSeq - XM_017026475
RefSeq - XM_017026476
RefSeq - XM_017026477
RefSeq - XM_017026478
RefSeq - XM_017026479
RefSeq - NM_001008701
RefSeq - NM_014921
RefSeq - XM_005259818
RefSeq - XM_011527796
RefSeq - XM_011527798
RefSeq Peptide - NP_001008701
RefSeq Peptide - NP_055736
swissprot - K7ERC3
swissprot - K7ESH3
swissprot - O94910
swissprot - K7EK47
Ensembl - ENSG00000072071
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgrl1aENSDARG00000089292Danio rerio
 CABZ01096573.1ENSDARG00000111704Danio rerio
 Adgrl1ENSMUSG00000013033Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRL2 / O95490 / adhesion G protein-coupled receptor L2ENSG0000011711463
ADGRL3 / Q9HAR2 / adhesion G protein-coupled receptor L3ENSG0000015047155
ADGRL4 / Q9HBW9 / adhesion G protein-coupled receptor L4ENSG0000016261816
ADGRE2 / Q9UHX3 / adhesion G protein-coupled receptor E2ENSG0000012750715
ADGRE5 / P48960 / adhesion G protein-coupled receptor E5ENSG0000012314615
ADGRD1 / Q6QNK2 / adhesion G protein-coupled receptor D1ENSG0000011145214
ADGRE3 / Q9BY15 / adhesion G protein-coupled receptor E3ENSG0000013135514
ADGRE1 / Q14246 / adhesion G protein-coupled receptor E1ENSG0000017483714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000203  GPS motif
 IPR000832  GPCR, family 2, secretin-like
 IPR000922  D-galactoside/L-rhamnose binding SUEL lectin domain
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR003112  Olfactomedin-like domain
 IPR003334  GPCR, family 2, latrophilin, C-terminal
 IPR003924  GPCR, family 2, latrophilin
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR031234  Latrophilin-1
 IPR032471  GAIN domain, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0035584 calcium-mediated signaling using intracellular calcium source ISS
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 biological_processGO:0090129 positive regulation of synapse maturation ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030426 growth cone ISS
 cellular_componentGO:0042734 presynaptic membrane ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0045202 synapse ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016524 latrotoxin receptor activity ISS
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0050839 cell adhesion molecule binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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