ENSG00000174837


Homo sapiens

Features
Gene ID: ENSG00000174837
  
Biological name :ADGRE1
  
Synonyms : ADGRE1 / adhesion G protein-coupled receptor E1 / Q14246
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 6887566
Gene end: 6940459
  
Corresponding Affymetrix probe sets: 207111_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000472553
Ensembl peptide - ENSP00000370814
Ensembl peptide - ENSP00000405974
Ensembl peptide - ENSP00000250572
Ensembl peptide - ENSP00000311545
Ensembl peptide - ENSP00000370811
NCBI entrez gene - 2015     See in Manteia.
OMIM - 600493
RefSeq - XM_011527794
RefSeq - NM_001256252
RefSeq - NM_001256253
RefSeq - NM_001256254
RefSeq - NM_001256255
RefSeq - NM_001974
RefSeq Peptide - NP_001243181
RefSeq Peptide - NP_001243182
RefSeq Peptide - NP_001243183
RefSeq Peptide - NP_001243184
RefSeq Peptide - NP_001965
swissprot - Q14246
swissprot - M0R2G7
Ensembl - ENSG00000174837
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adgre10ENSDARG00000075855Danio rerio
 adgre14ENSDARG00000056062Danio rerio
 adgre15ENSDARG00000096588Danio rerio
 adgre16ENSDARG00000096622Danio rerio
 adgre17ENSDARG00000095297Danio rerio
 adgre18ENSDARG00000096644Danio rerio
 adgre19ENSDARG00000096649Danio rerio
 adgre6ENSDARG00000095494Danio rerio
 adgre7ENSDARG00000041399Danio rerio
 adgre8ENSDARG00000079050Danio rerio
 adgre9ENSDARG00000096577Danio rerio
 Adgre1ENSMUSG00000004730Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADGRE2 / Q9UHX3 / adhesion G protein-coupled receptor E2ENSG0000012750731
ADGRE3 / Q9BY15 / adhesion G protein-coupled receptor E3ENSG0000013135528
ADGRE5 / P48960 / adhesion G protein-coupled receptor E5ENSG0000012314626
ADGRL3 / Q9HAR2 / adhesion G protein-coupled receptor L3ENSG0000015047124
ADGRL1 / O94910 / adhesion G protein-coupled receptor L1ENSG0000007207123
ADGRL2 / O95490 / adhesion G protein-coupled receptor L2ENSG0000011711422
ADGRD1 / Q6QNK2 / adhesion G protein-coupled receptor D1ENSG0000011145220
ADGRL4 / Q9HBW9 / adhesion G protein-coupled receptor L4ENSG0000016261820


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000203  GPS motif
 IPR000742  EGF-like domain
 IPR000832  GPCR, family 2, secretin-like
 IPR001740  GPCR family 2, EMR1-like receptor
 IPR001881  EGF-like calcium-binding domain
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR013032  EGF-like, conserved site
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR026823  Complement Clr-like EGF domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0071944 cell periphery IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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