ENSG00000131435


Homo sapiens

Features
Gene ID: ENSG00000131435
  
Biological name :PDLIM4
  
Synonyms : P50479 / PDLIM4 / PDZ and LIM domain 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q31.1
Gene start: 132257671
Gene end: 132273454
  
Corresponding Affymetrix probe sets: 211564_s_at (Human Genome U133 Plus 2.0 Array)   214174_s_at (Human Genome U133 Plus 2.0 Array)   214175_x_at (Human Genome U133 Plus 2.0 Array)   218690_at (Human Genome U133 Plus 2.0 Array)   218691_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000253754
Ensembl peptide - ENSP00000411753
Ensembl peptide - ENSP00000368303
NCBI entrez gene - 8572     See in Manteia.
OMIM - 603422
RefSeq - NM_003687
RefSeq - XM_017010002
RefSeq - NM_001131027
RefSeq Peptide - NP_001124499
RefSeq Peptide - NP_003678
swissprot - A0A0S2Z4N4
swissprot - P50479
swissprot - C9J542
Ensembl - ENSG00000131435
  
Related genetic diseases (OMIM): 166710 - {Osteoporosis, susceptibility to}, 166710
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdlim4ENSDARG00000068973Danio rerio
 PDLIM4ENSGALG00000039872Gallus gallus
 P70271ENSMUSG00000020388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O00151 / PDLIM1 / PDZ and LIM domain 1ENSG0000010743845
PDLIM3 / Q53GG5 / PDZ and LIM domain 3ENSG0000015455344
PDLIM2 / Q96JY6 / PDZ and LIM domain 2ENSG0000012091333


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR001781  Zinc finger, LIM-type
 IPR031847  Domain of unknown function DUF4749
 IPR036034  PDZ superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031532 actin cytoskeleton reorganization IDA
 biological_processGO:0098976 excitatory chemical synaptic transmission ISS
 cellular_componentGO:0001725 stress fiber IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0031905 early endosome lumen ISS
 cellular_componentGO:0031941 filamentous actin IDA
 cellular_componentGO:0034777 recycling endosome lumen ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043197 dendritic spine ISS
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051393 alpha-actinin binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr