ENSG00000131730


Homo sapiens

Features
Gene ID: ENSG00000131730
  
Biological name :CKMT2
  
Synonyms : CKMT2 / creatine kinase, mitochondrial 2 / P17540
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q14.1
Gene start: 81233285
Gene end: 81266397
  
Corresponding Affymetrix probe sets: 205295_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000254035
Ensembl peptide - ENSP00000427635
Ensembl peptide - ENSP00000423264
Ensembl peptide - ENSP00000410289
Ensembl peptide - ENSP00000404203
NCBI entrez gene - 1160     See in Manteia.
OMIM - 123295
RefSeq - NM_001099735
RefSeq - NM_001099736
RefSeq - NM_001825
RefSeq Peptide - NP_001093206
RefSeq Peptide - NP_001816
RefSeq Peptide - NP_001093205
swissprot - P17540
swissprot - D6R998
swissprot - A0A024RAK5
swissprot - D6RHV3
Ensembl - ENSG00000131730
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ckmt2aENSDARG00000069615Danio rerio
 ckmt2bENSDARG00000039929Danio rerio
 CKMT2ENSGALG00000015602Gallus gallus
 Ckmt2ENSMUSG00000021622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CKMT1A / P12532 / creatine kinase, mitochondrial 1AENSG0000022357279
CKMT1B / P12532 / creatine kinase, mitochondrial 1BENSG0000023728979
CKB / P12277 / creatine kinase BENSG0000016616559
CKM / P06732 / creatine kinase, M-typeENSG0000010487958


Protein motifs (from Interpro)
Interpro ID Name
 IPR000749  ATP:guanido phosphotransferase
 IPR014746  Glutamine synthetase/guanido kinase, catalytic domain
 IPR022413  ATP:guanido phosphotransferase, N-terminal
 IPR022414  ATP:guanido phosphotransferase, catalytic domain
 IPR022415  ATP:guanido phosphotransferase active site
 IPR036802  ATP:guanido phosphotransferase, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006600 creatine metabolic process TAS
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005743 mitochondrial inner membrane TAS
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004111 creatine kinase activity TAS
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016772 transferase activity, transferring phosphorus-containing groups IEA


Pathways (from Reactome)
Pathway description
Creatine metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131730 CKMT2 / P17540 / creatine kinase, mitochondrial 2  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr