ENSG00000166165


Homo sapiens

Features
Gene ID: ENSG00000166165
  
Biological name :CKB
  
Synonyms : CKB / creatine kinase B / P12277
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q32.33
Gene start: 103519659
Gene end: 103523111
  
Corresponding Affymetrix probe sets: 200884_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451904
Ensembl peptide - ENSP00000451680
Ensembl peptide - ENSP00000451686
Ensembl peptide - ENSP00000299198
Ensembl peptide - ENSP00000450676
Ensembl peptide - ENSP00000451426
Ensembl peptide - ENSP00000451611
NCBI entrez gene - 1152     See in Manteia.
OMIM - 123280
RefSeq - XM_017020952
RefSeq - NM_001823
RefSeq - XM_017020951
RefSeq Peptide - NP_001814
swissprot - H0YJJ7
swissprot - H0YJK0
swissprot - G3V2I1
swissprot - P12277
swissprot - V9HWH2
swissprot - G3V461
swissprot - H0YJG0
swissprot - G3V4N7
Ensembl - ENSG00000166165
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ckbaENSDARG00000069752Danio rerio
 ckbbENSDARG00000043257Danio rerio
 CKBENSGALG00000011511Gallus gallus
 CkbENSMUSG00000001270Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CKM / P06732 / creatine kinase, M-typeENSG0000010487981
CKMT1A / P12532 / creatine kinase, mitochondrial 1AENSG0000022357267
CKMT1B / P12532 / creatine kinase, mitochondrial 1BENSG0000023728967
CKMT2 / P17540 / creatine kinase, mitochondrial 2ENSG0000013173065


Protein motifs (from Interpro)
Interpro ID Name
 IPR000749  ATP:guanido phosphotransferase
 IPR014746  Glutamine synthetase/guanido kinase, catalytic domain
 IPR022413  ATP:guanido phosphotransferase, N-terminal
 IPR022414  ATP:guanido phosphotransferase, catalytic domain
 IPR022415  ATP:guanido phosphotransferase active site
 IPR036802  ATP:guanido phosphotransferase, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006600 creatine metabolic process TAS
 biological_processGO:0007420 brain development IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0021549 cerebellum development IEA
 biological_processGO:0021762 substantia nigra development HEP
 biological_processGO:0030644 cellular chloride ion homeostasis IEA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004111 creatine kinase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016772 transferase activity, transferring phosphorus-containing groups IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI


Pathways (from Reactome)
Pathway description
Creatine metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000104879 CKM / P06732 / creatine kinase, M-type  / complex
 ENSG00000166165 CKB / P12277 / creatine kinase B  / complex






 

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