ENSG00000132141


Homo sapiens

Features
Gene ID: ENSG00000132141
  
Biological name :CCT6B
  
Synonyms : CCT6B / chaperonin containing TCP1 subunit 6B / Q92526
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 34927859
Gene end: 34981078
  
Corresponding Affymetrix probe sets: 206587_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327191
Ensembl peptide - ENSP00000398044
Ensembl peptide - ENSP00000400917
Ensembl peptide - ENSP00000462020
NCBI entrez gene - 10693     See in Manteia.
OMIM - 610730
RefSeq - XM_017024024
RefSeq - NM_001193529
RefSeq - NM_001193530
RefSeq - NM_006584
RefSeq - XM_011524203
RefSeq - XM_017024023
RefSeq Peptide - NP_006575
RefSeq Peptide - NP_001180458
RefSeq Peptide - NP_001180459
swissprot - Q92526
swissprot - J3KRI6
Ensembl - ENSG00000132141
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cct6aENSDARG00000021252Danio rerio
 CCT6AENSGALG00000002448Gallus gallus
 Cct6bENSMUSG00000020698Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCT6A / P40227 / chaperonin containing TCP1 subunit 6AENSG0000014673185


Protein motifs (from Interpro)
Interpro ID Name
 IPR002194  Chaperonin TCP-1, conserved site
 IPR002423  Chaperonin Cpn60/TCP-1 family
 IPR012722  T-complex protein 1, zeta subunit
 IPR017998  Chaperone tailless complex polypeptide 1 (TCP-1)
 IPR027409  GroEL-like apical domain superfamily
 IPR027410  TCP-1-like chaperonin intermediate domain superfamily
 IPR027413  GroEL-like equatorial domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding TAS
 biological_processGO:0006458 "de novo" protein folding IBA
 biological_processGO:0007283 spermatogenesis TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0051131 chaperone-mediated protein complex assembly TAS
 biological_processGO:0061077 chaperone-mediated protein folding IBA
 biological_processGO:1901998 toxin transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005832 chaperonin-containing T-complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008565 protein transporter activity TAS
 molecular_functionGO:0044183 protein binding involved in protein folding IBA
 molecular_functionGO:0051082 unfolded protein binding IBA


Pathways (from Reactome)
Pathway description
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Folding of actin by CCT/TriC
Association of TriC/CCT with target proteins during biosynthesis
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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